ENSMUSG00000037966


Mus musculus

Features
Gene ID: ENSMUSG00000037966
  
Biological name :Ninj1
  
Synonyms : Ninj1 / ninjurin 1 / O70131
  
Possible biological names infered from orthology : Q92982
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 49187485
Gene end: 49196244
  
Corresponding Affymetrix probe sets: 10404996 (MoGene1.0st)   1438928_x_at (Mouse Genome 430 2.0 Array)   1441281_s_at (Mouse Genome 430 2.0 Array)   1447549_x_at (Mouse Genome 430 2.0 Array)   1448417_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000036740
Ensembl peptide - ENSMUSP00000121186
Ensembl peptide - ENSMUSP00000114130
NCBI entrez gene - 18081     See in Manteia.
MGI - MGI:1196617
RefSeq - NM_013610
RefSeq Peptide - NP_038638
swissprot - D3YW25
swissprot - D6RFN5
swissprot - O70131
swissprot - Q3TXT8
Ensembl - ENSMUSG00000037966
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NINJ1ENSDARG00000103663Danio rerio
 NINJ1ENSGALG00000026891Gallus gallus
 NINJ1ENSG00000131669Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ninj2 / Q9JL89 / Mus musculus ninjurin 2 (Ninj2), transcript variant 2, mRNA. / Q9NZG7* / ninjurin 2*ENSMUSG0000004137740


Protein motifs (from Interpro)
Interpro ID Name
 IPR007007  Ninjurin
 IPR015639  Ninjurin1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0042246 tissue regeneration IEA
 biological_processGO:1990384 hyaloid vascular plexus regression IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Ryr2tm2Hhv/Ryr2+
Genetic Background: involves: 129 * C57BL/6

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ryr2tm2Hhv/Ryr2+
Genetic Background: involves: 129 * C57BL/6

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

Allelic Composition: Ninj1tm1Gto/Ninj1tm1Gto
Genetic Background: B6.129P2-Ninj1tm1Gto

 MP:0002007 increased sensitivity to gamma-irradiation "increased incidence of cell death following high levels of gamma-irradiation" [J:51834]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Edn2tm1Ywa/Edn2tm1Ywa
Genetic Background: involves: 129S6/SvEvTac

 MP:0002442 abnormal leukocyte physiology "abnormal function of any of the white blood cells (basophils, eosinophils, neutrophils, lymphocytes, or monocytes) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ryr2tm2Hhv/Ryr2+
Genetic Background: involves: 129 * C57BL/6

 MP:0003628 abnormal lymphocyte adhesion "anomaly in the number of or process by which lymphocytes adhere to the luminal aspects of high endothelial venules prior to transmigration out of the vessel" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95656]
Show

Allelic Composition: Ninj1tm1Gto/Ninj1tm1Gto
Genetic Background: B6.129P2-Ninj1tm1Gto

 MP:0003799 impaired macrophage migration "defect in the ability of macrophages to move up a chemotactic gradient" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ninj1tm1Gto/Ninj1tm1Gto
Genetic Background: B6.129P2-Ninj1tm1Gto

 MP:0004800 decreased susceptibility to experimental autoimmune encephalomyelitis "reduced likelihood that an organism will develop disease symptoms similar to human multiple sclerosis upon induction with antigens to Myelin Basic Protein (MBP), Proteolipid Protein (PLP), and/or Myelin Oligodendrocyte glycoprotein (MOG)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ninj1tm1Gto/Ninj1tm1Gto
Genetic Background: B6.129P2-Ninj1tm1Gto

Allelic Composition: Ninj1tm1Gto/Ninj1+
Genetic Background: B6.129P2-Ninj1tm1Gto

 MP:0008007 abnormal cellular replicative senescence "anomaly in the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [GO:0001302, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex19.1tm1.2Ics/Tex19.1tm1.2Ics
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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