ENSMUSG00000038047


Mus musculus

Features
Gene ID: ENSMUSG00000038047
  
Biological name :Haus6
  
Synonyms : Haus6 / HAUS augmin like complex subunit 6
  
Possible biological names infered from orthology : Q7Z4H7
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: C4
Gene start: 86578855
Gene end: 86612055
  
Corresponding Affymetrix probe sets: 10514201 (MoGene1.0st)   1429665_at (Mouse Genome 430 2.0 Array)   1455488_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070504
Ensembl peptide - ENSMUSP00000118609
NCBI entrez gene - 230376     See in Manteia.
MGI - MGI:1923389
RefSeq - XM_011250011
RefSeq - NM_173400
RefSeq - XM_006537875
RefSeq - XM_011250010
RefSeq Peptide - NP_775576
swissprot - B1AXR2
swissprot - Q6NV99
Ensembl - ENSMUSG00000038047
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 haus6ENSDARG00000101652Danio rerio
 HAUS6ENSGALG00000015091Gallus gallus
 HAUS6ENSG00000147874Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026797  HAUS augmin-like complex subunit 6
 IPR028163  HAUS augmin-like complex subunit 6, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007098 centrosome cycle ISO
 biological_processGO:0051225 spindle assembly ISO
 cellular_componentGO:0005813 centrosome ISO
 cellular_componentGO:0005815 microtubule organizing center ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0070652 HAUS complex ISO
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Csgalnact1tm1Nari/Csgalnact1tm1Nari,Csgalnact2tm1.1Staka/Csgalnact2tm1.1Staka,Tg(Col2a1-cre)1Bhr/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL

 MP:0009760 abnormal mitotic spindle "an anomaly in the formation of the ellipsoidal (bipolar) collection of fibers visible during nuclear division and cytokinesis responsible for accurate segregation of chromosomes during mitosis" [ISBN:8185198691 "Rieger R et al Eds Glossary of Genetics Classical and Molecular"]
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Allelic Composition: Csgalnact1tm1Nari/Csgalnact1tm1Nari,Csgalnact2tm1.1Staka/Csgalnact2tm1.1Staka,Tg(Col2a1-cre)1Bhr/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Csgalnact1tm1Nari/Csgalnact1tm1Nari,Csgalnact2tm1.1Staka/Csgalnact2tm1.1Staka,Tg(Col2a1-cre)1Bhr/0
Genetic Background: involves: C57BL/6 * C57BL/6J * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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