ENSMUSG00000038085


Mus musculus

Features
Gene ID: ENSMUSG00000038085
  
Biological name :Cnbd2
  
Synonyms : Cnbd2 / Cyclic nucleotide-binding domain-containing protein 2 / Q9D5U8
  
Possible biological names infered from orthology : cyclic nucleotide binding domain containing 2 / Q96M20
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 156312299
Gene end: 156375638
  
Corresponding Affymetrix probe sets: 10477831 (MoGene1.0st)   1425047_a_at (Mouse Genome 430 2.0 Array)   1430069_at (Mouse Genome 430 2.0 Array)   1432391_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105208
Ensembl peptide - ENSMUSP00000041268
Ensembl peptide - ENSMUSP00000073598
NCBI entrez gene - 70873     See in Manteia.
MGI - MGI:1918123
RefSeq - XM_006500172
RefSeq - NM_001316755
RefSeq - NM_027585
RefSeq - XM_006500167
RefSeq - XM_006500170
RefSeq Peptide - NP_081861
RefSeq Peptide - NP_001303684
swissprot - A2AV96
swissprot - Q9D5U8
swissprot - A2AV95
Ensembl - ENSMUSG00000038085
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CNBD2ENSG00000149646Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007283 spermatogenesis IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0030552 cAMP binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0004850 abnormal testis weight "anomaly in the average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0009831 abnormal sperm midpiece morphology "any structural abnormality of the highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece" [PMID:14581499]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

 MP:0013209 abnormal motile cilium physiology "any structural anomaly of a cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface; motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues and may also function as sensory organelles" [GO:0031514]
Show

Allelic Composition: Grk5tm1Rjl/Grk5tm1Rjl
Genetic Background: involves: 129S4/SvJaeSor

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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