ENSMUSG00000038178


Mus musculus

Features
Gene ID: ENSMUSG00000038178
  
Biological name :Slc43a2
  
Synonyms : Q8CGA3 / Slc43a2 / solute carrier family 43, member 2
  
Possible biological names infered from orthology : Q8N370
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B5
Gene start: 75531694
Gene end: 75577575
  
Corresponding Affymetrix probe sets: 10378649 (MoGene1.0st)   1434308_at (Mouse Genome 430 2.0 Array)   1439965_at (Mouse Genome 430 2.0 Array)   1456940_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046074
Ensembl peptide - ENSMUSP00000104071
Ensembl peptide - ENSMUSP00000116255
Ensembl peptide - ENSMUSP00000123101
Ensembl peptide - ENSMUSP00000126838
Ensembl peptide - ENSMUSP00000117264
NCBI entrez gene - 215113     See in Manteia.
MGI - MGI:2442746
RefSeq - XM_006532828
RefSeq - NM_001199283
RefSeq - NM_001199284
RefSeq - NM_173388
RefSeq - XM_006532821
RefSeq - XM_006532822
RefSeq - XM_006532823
RefSeq - XM_006532824
RefSeq - XM_006532825
RefSeq - XM_006532826
RefSeq - XM_006532827
RefSeq - XM_006532819
RefSeq - XM_006532820
RefSeq Peptide - NP_775564
RefSeq Peptide - NP_001186213
RefSeq Peptide - NP_001186212
swissprot - Q8CGA3
swissprot - Q5ND24
swissprot - Q5ND23
swissprot - Q5ND25
Ensembl - ENSMUSG00000038178
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc43a2aENSDARG00000036848Danio rerio
 slc43a2bENSDARG00000061120Danio rerio
 SLC43A2ENSGALG00000002783Gallus gallus
 Q8N370ENSG00000167703Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BSM7 / Slc43a1 / solute carrier family 43, member 1 / O75387*ENSMUSG0000002707557
A2AVZ9 / Slc43a3 / Solute carrier family 43 member 3 / Q8NBI5*ENSMUSG0000002707418


Protein motifs (from Interpro)
Interpro ID Name
 IPR011701  Major facilitator superfamily
 IPR020846  Major facilitator superfamily domain
 IPR027201  Large neutral amino acids transporter small subunit 4
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015804 neutral amino acid transport IEA
 biological_processGO:0015807 L-amino acid transport IDA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1902475 L-alpha-amino acid transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015175 neutral amino acid transmembrane transporter activity IBA
 molecular_functionGO:0015179 L-amino acid transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000188 abnormal circulating glucose level "anomalous concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0000609 abnormal liver physiology "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0001666 abnormal nutrient absorption "anomalous ability of the body to take in constituents of food necessary for normal physiologic function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0001860 liver inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0003979 increased circulating carnitine level "greater than normal blood concentration of this quaternary ammonium amino acid derivative involved in transport of fatty acids across the mitochondrial membrane" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0004201 fetal growth retardation "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0004265 abnormal placental transport "anomaly in the conveyance of metabolic products and nutrients across the placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0005281 increased fatty acid level "higher than normal non-circulating level of organic, monobasic acids derived from hydrocarbons; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0005311 abnormal circulating amino acid level "aberrant concentration in the blood of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:83263]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0005332 abnormal amino acid level "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0008489 postnatal slow weight gain "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0009431 decreased fetal weight "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0012172 abnormal amniotic fluid composition "any alteration in the expected chemical makeup of the watery liquid within the amnion that surrounds and cushions a growing fetus; normally, early in gestation, amniotic fluid is similar to maternal plasma, mainly water with electrolytes, and later in gestation, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid" [MGI:anna]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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