| MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0000064 | failure of secondary bone resorption | "inability of osteoclasts to degrade the organic and inorganic phases of bone by absorption" [J:67040, J:61295] |
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Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0000067 | osteopetrosis | "excessive formation of dense trabecular bone and excessive calcified cartilage formation; may lead to anemia and extramedullary hematopoiesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0000121 | failure of tooth eruption | "inability of the teeth to grow into the oral cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0000125 | absent incisors | "missing long pointed teeth; most anterior and prominent in the jaw" [J:17489] |
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Allelic Composition: Ostm1gl/Ostm1om
Genetic Background: involves: C3HeB/FeJ
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| MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0000183 | decreased circulating LDL cholesterol level | "less than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0000455 | abnormal maxilla morphology | "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0000559 | abnormal femur morphology | "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0001290 | delayed eyelid opening | "late average time for the first postnatal eye opening" [J:17792] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0001851 | eye inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the eye" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
Allelic Composition: Ostm1gl/Ostm1om
Genetic Background: involves: C3HeB/FeJ
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
Allelic Composition: Ostm1gl/Ostm1om
Genetic Background: involves: C3HeB/FeJ
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0002113 | abnormal skeleton development | "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0002644 | decreased circulating triglyceride level | "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0002689 | abnormal molar morphology | "structural defect of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [il:Ira Lu , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0002874 | decreased hemoglobin content | "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0002968 | increased circulating alkaline phosphatase level | "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
|
| MP:0003109 | short femur | "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0003723 | abnormal long bone morphology | "malformation of any of the several elongated bones of the extremities
" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0003797 | abnormal compact bone morphology | "structural anomaly of the outer layers of solid, hard bone that covers spongy bone; consists of parallel osteons containing mineral deposits and interstitial lamellae" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0003932 | abnormal molar crown morphology | "defects in the upper part of the molar, which is normally covered with enamel " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0003961 | decreased lean body mass | "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0004353 | abnormal deltoid tuberosity morphology | "any structural anomaly of a rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0004830 | short incisors | "reduced length of the long pointed teeth; most anterior and prominent in the jaw" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0005150 | cachexia | "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0005358 | abnormal incisor morphology | "structural defect of the long pointed teeth; most anterior and prominent in the jaw" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85574] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0008274 | failure of bone ossification | "failure to initiate or a block in the process of the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0011084 | partial lethality at weaning | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms at weaning age" [MGI:csmith] |
Show
Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0030089 | short lower incisors | "reduced length of the lower set of long teeth that are the most anterior and prominent in the jaw" [MGI:anna] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0030236 | abnormal mental foramen morphology | "any structural anomaly of the small opening located on the anterior surface of the mandible; the mental nerve, a terminal branch of inferior alveolar nerve, and the mental artery leave the mandibular canal through it" [https://radiopaedia.org/articles/mental-foramen-1] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0030302 | abnormal maxillary zygomatic process morphology | "any structural anomaly of the rough triangular eminence situated at the angle of separation of the anterior, zygomatic, and orbital surfaces; in front, it forms part of the anterior surface; behind, it is concave, and forms part of the infratemporal fossa; above, it is rough and serrated for articulation with the zygomatic bone; below, it presents the prominent arched border which marks the division between the anterior and infratemporal surfaces" [https://en.wikipedia.org/wiki/Zygomatic_process_of_maxilla] |
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Allelic Composition: Ostm1om/Ostm1om
Genetic Background: C3HeB/FeJ-Ostm1om
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| MP:0030451 | abnormal dentin mineralization | "anomaly in the process by which calcium salts are deposited into dentin" [GO:0097188] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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| MP:0030494 | abnormal molar root morphology | "any structural anomaly of the part of a molar tooth that is implanted in the gum" [MGI:anna] |
Show
Allelic Composition: Traf2tm1Mak/Traf2tm1Mak
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6J)
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