ENSMUSG00000038357


Mus musculus

Features
Gene ID: ENSMUSG00000038357
  
Biological name :Camp
  
Synonyms : Camp / Cathelicidin antimicrobial peptide Cathelin-related antimicrobial peptide / P51437
  
Possible biological names infered from orthology : cathelicidin antimicrobial peptide
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F2
Gene start: 109847379
Gene end: 109849617
  
Corresponding Affymetrix probe sets: 10597098 (MoGene1.0st)   1419691_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107653
NCBI entrez gene - 12796     See in Manteia.
MGI - MGI:108443
RefSeq - NM_009921
RefSeq Peptide - NP_034051
swissprot - P51437
Ensembl - ENSMUSG00000038357
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CATH3ENSGALG00000034150Gallus gallus
 CATHL1ENSGALG00000027973Gallus gallus
 CATHL2ENSGALG00000019696Gallus gallus
 CAMPENSG00000164047Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001894  Cathelicidin
 IPR018216  Cathelicidin, conserved site
 IPR022746  Cathelicidin, antimicrobial peptide, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0002227 innate immune response in mucosa ISO
 biological_processGO:0006952 defense response IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0019731 antibacterial humoral response ISO
 biological_processGO:0042742 defense response to bacterium ISO
 biological_processGO:0044130 negative regulation of growth of symbiont in host IMP
 biological_processGO:0044140 negative regulation of growth of symbiont on or near host surface ISO
 biological_processGO:0045087 innate immune response IMP
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IEA
 biological_processGO:0050830 defense response to Gram-positive bacterium IEA
 biological_processGO:0051873 killing by host of symbiont cells ISO
 biological_processGO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide IMP
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071224 cellular response to peptidoglycan IEA
 biological_processGO:0071347 cellular response to interleukin-1 IEA
 biological_processGO:0071354 cellular response to interleukin-6 IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0042581 specific granule ISO
 cellular_componentGO:0042995 cell projection IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Afdntm1Ytk/Afdntm1Ytk
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001313 increased incidence of corneal inflammation "greater than average and persistent occurrence of corneal irritation" [J:4606]
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Allelic Composition: Afdntm1Ytk/Afdntm1Ytk
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Afdntm1Ytk/Afdntm1Ytk
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Camptm1Rlg/Camp+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Camptm1Rlg/Camptm1Rlg
Genetic Background: 129X1/SvJ-Camptm1Rlg

 MP:0005399 increased susceptibility to fungal infection "greater likelihood that an organism will develop ill effects from infection by a yeast or mold, or from components of, or toxins produced by, these organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Afdntm1Ytk/Afdntm1Ytk
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

 MP:0008127 decreased dendritic cell number "reduction in the number of a cells of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation" [ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pmp22Tr-2J/Pmp22+
Genetic Background: C57BL/6J-Pmp22Tr-2J/GrsrJ

 MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Camptm1Rlg/Camptm1Rlg
Genetic Background: 129X1/SvJ-Camptm1Rlg

 MP:0011518 abnormal cell chemotaxis "any anomaly in the directed movement of a motile cell guided by a specific chemical concentration gradient; movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)" [GO:0060326]
Show

Allelic Composition: Pmp22Tr-2J/Pmp22+
Genetic Background: C57BL/6J-Pmp22Tr-2J/GrsrJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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