ENSMUSG00000038776


Mus musculus

Features
Gene ID: ENSMUSG00000038776
  
Biological name :Ephx1
  
Synonyms : Ephx1 / Epoxide hydrolase 1 / Q9D379
  
Possible biological names infered from orthology : P07099
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H4
Gene start: 180976210
Gene end: 181020904
  
Corresponding Affymetrix probe sets: 10360684 (MoGene1.0st)   1422438_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122671
Ensembl peptide - ENSMUSP00000047551
Ensembl peptide - ENSMUSP00000106697
Ensembl peptide - ENSMUSP00000114363
NCBI entrez gene - 13849     See in Manteia.
MGI - MGI:95405
RefSeq - NM_001312918
RefSeq - NM_010145
RefSeq Peptide - NP_001299847
RefSeq Peptide - NP_034275
swissprot - Q9D379
swissprot - D3Z4M3
swissprot - E9PWK1
swissprot - F6YTS6
Ensembl - ENSMUSG00000038776
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ephx1ENSDARG00000042854Danio rerio
 EPHX1ENSGALG00000009291Gallus gallus
 EPHX1ENSG00000143819Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR000639  Epoxide hydrolase-like
 IPR010497  Epoxide hydrolase, N-terminal
 IPR016292  Epoxide hydrolase
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006725 cellular aromatic compound metabolic process IMP
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0014070 response to organic cyclic compound IMP
 biological_processGO:0019439 aromatic compound catabolic process IEA
 biological_processGO:0034312 diol biosynthetic process IEA
 biological_processGO:0071310 cellular response to organic substance IEA
 biological_processGO:0071385 cellular response to glucocorticoid stimulus IEA
 biological_processGO:0097176 epoxide metabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004301 epoxide hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0033961 cis-stilbene-oxide hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004502 decreased incidence of chemically-induced tumors "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: En2tm2Alj/En2tm2Alj
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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