ENSMUSG00000038880


Mus musculus

Features
Gene ID: ENSMUSG00000038880
  
Biological name :Mrps34
  
Synonyms : 28S ribosomal protein S34, mitochondrial / Mrps34 / Q9JIK9
  
Possible biological names infered from orthology : mitochondrial ribosomal protein S34 / P82930
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.3
Gene start: 24895116
Gene end: 24897502
  
Corresponding Affymetrix probe sets: 10442638 (MoGene1.0st)   10442643 (MoGene1.0st)   1421971_a_at (Mouse Genome 430 2.0 Array)   1448905_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045111
Ensembl peptide - ENSMUSP00000120985
NCBI entrez gene - 79044     See in Manteia.
MGI - MGI:1930188
RefSeq - NM_023260
RefSeq Peptide - NP_075749
swissprot - Q9JIK9
Ensembl - ENSMUSG00000038880
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mrps34ENSDARG00000057910Danio rerio
 MRPS34ENSGALG00000001792Gallus gallus
 MRPS34ENSG00000074071Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR032053  Mitochondrial 28S ribosomal protein S34


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032543 mitochondrial translation IMP
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005763 mitochondrial small ribosomal subunit ISS
 cellular_componentGO:0005840 ribosome IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003735 structural constituent of ribosome IEA


Pathways (from Reactome)
Pathway description
Mitochondrial translation elongation
Mitochondrial translation termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0001625 cardiac hypertrophy "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0002941 increased circulating alanine transaminase level "increased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0003333 liver fibrosis "invasion of fibrous connective tissue into the liver, often resulting from inflammation or injury " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0005290 decreased oxygen consumption "less than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0005599 increased cardiac muscle contractility "greater than the normal ability of the heart muscle to shorten or to develop increased tension " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0009404 centrally nucleated skeletal muscle fibers "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0010956 abnormal mitochondrial ATP synthesis coupled electron transport "anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

 MP:0013272 abnormal translation "any anomaly in the cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain; translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA; translation ends with the release of a polypeptide chain from the ribosome" [GO:0006412]
Show

Allelic Composition: Serpine1tm1Mlg/Serpine1tm1Mlg
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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