ENSMUSG00000039205


Mus musculus

Features
Gene ID: ENSMUSG00000039205
  
Biological name :Ciz1
  
Synonyms : CDKN1A interacting zinc finger protein 1 / Ciz1
  
Possible biological names infered from orthology : Q9ULV3
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 32352327
Gene end: 32380970
  
Corresponding Affymetrix probe sets: 10471387 (MoGene1.0st)   1448779_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120295
Ensembl peptide - ENSMUSP00000120019
Ensembl peptide - ENSMUSP00000122469
Ensembl peptide - ENSMUSP00000141211
Ensembl peptide - ENSMUSP00000048428
Ensembl peptide - ENSMUSP00000108957
Ensembl peptide - ENSMUSP00000108958
Ensembl peptide - ENSMUSP00000108960
Ensembl peptide - ENSMUSP00000108964
Ensembl peptide - ENSMUSP00000116812
Ensembl peptide - ENSMUSP00000117937
Ensembl peptide - ENSMUSP00000119429
NCBI entrez gene - 68379     See in Manteia.
MGI - MGI:1920234
RefSeq - XM_011239169
RefSeq - XM_006498271
RefSeq - XM_006498272
RefSeq - XM_006498273
RefSeq - XM_006498274
RefSeq - XM_006498275
RefSeq - XM_006498276
RefSeq - XM_006498277
RefSeq - XM_006498278
RefSeq - XM_006498279
RefSeq - XM_006498280
RefSeq - XM_006498281
RefSeq - XM_006498282
RefSeq - XM_006498283
RefSeq - XM_006498285
RefSeq - XM_011239168
RefSeq - NM_001252534
RefSeq - NM_001252536
RefSeq - NM_001252537
RefSeq - NM_001252538
RefSeq - NM_028412
RefSeq Peptide - NP_001239466
RefSeq Peptide - NP_001239467
RefSeq Peptide - NP_082688
RefSeq Peptide - NP_001239463
RefSeq Peptide - NP_001239465
swissprot - F7D5G9
swissprot - A0A0A6YVQ0
swissprot - A0A0A0MQJ7
swissprot - A2AN61
swissprot - Q3UUV0
swissprot - Q8VEH2
swissprot - F6S5B6
swissprot - F6XWQ4
swissprot - F7AT58
swissprot - F7BM53
Ensembl - ENSMUSG00000039205
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ciz1aENSDARG00000089781Danio rerio
 CIZ1ENSGALG00000042325Gallus gallus
 CIZ1ENSG00000148337Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000690  Matrin/U1-C, C2H2-type zinc finger
 IPR003604  Matrin/U1-C-like, C2H2-type zinc finger
 IPR011989  Armadillo-like helical
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR022755  Zinc finger, double-stranded RNA binding
 IPR026939  At2g23090-like
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032298 positive regulation of DNA-dependent DNA replication initiation IGI
 biological_processGO:0051457 maintenance of protein location in nucleus IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0000708 thymus hyperplasia "increased cell number in the thymus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0001353 increased aggression to other mice "when compared to controls, subjects exhibit greater than the normal level of domineering, assaultive posture and/or hostile physical action toward other mice" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Webster s II New College Dictionary:ISBN 0-395-70869-9]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0001407 short stride length "reduced average distance between steps" [J:34193]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ttntm2.1Hgra/Ttntm2.1Hgra
Genetic Background: B6J.Cg-Ttntm2.1Hgra

 MP:0008102 lymph node hyperplasia "overdevelopment or increased size, usually due to increased cell number, in the lymph nodes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0008409 increased cellular sensitivity to hydroxyurea "greater incidence of cell death following exposure to hydroxyurea" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0012563 increased tumor incidence following infection "greater than the expected number of neoplasms in a specific population after infection with a pathogen in a given time period, usually of a specific type" [http://orcid.org/0000-0001-5208-3432]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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