ENSMUSG00000039208


Mus musculus

Features
Gene ID: ENSMUSG00000039208
  
Biological name :Metrnl
  
Synonyms : Meteorin-like protein / Metrnl / Q8VE43
  
Possible biological names infered from orthology : meteorin like, glial cell differentiation regulator / Q641Q3
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 121701544
Gene end: 121716306
  
Corresponding Affymetrix probe sets: 10383615 (MoGene1.0st)   1424356_a_at (Mouse Genome 430 2.0 Array)   1441903_x_at (Mouse Genome 430 2.0 Array)   1444097_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101695
Ensembl peptide - ENSMUSP00000122949
Ensembl peptide - ENSMUSP00000038126
NCBI entrez gene - 210029     See in Manteia.
MGI - MGI:2384806
RefSeq - NM_144797
RefSeq Peptide - NP_659046
swissprot - A2AAV6
swissprot - Q8VE43
Ensembl - ENSMUSG00000039208
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 metrnlENSDARG00000101914Danio rerio
 si:dkey-27j5.3ENSDARG00000007289Danio rerio
 METRNLENSGALG00000028354Gallus gallus
 METRNLENSG00000176845Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Metrn / Q8C1Q4 / meteorin, glial cell differentiation regulator / Q9UJH8*ENSMUSG0000000227439


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009409 response to cold IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014850 response to muscle activity IDA
 biological_processGO:0045444 fat cell differentiation IDA
 biological_processGO:0050728 negative regulation of inflammatory response IDA
 biological_processGO:0050873 brown fat cell differentiation IDA
 biological_processGO:0090336 positive regulation of brown fat cell differentiation IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Memo1tm1b(EUCOMM)Wtsi/Memo1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Memo1tm1b(EUCOMM)Wtsi/Bay

 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Memo1tm1b(EUCOMM)Wtsi/Memo1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Memo1tm1b(EUCOMM)Wtsi/Bay

 MP:0010101 increased sacral vertebrae number "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Memo1tm1b(EUCOMM)Wtsi/Memo1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Memo1tm1b(EUCOMM)Wtsi/Bay

 MP:0013026 decreased Ly6C low monocyte number "decrease in the number of monocytes that express low levels of Ly6C and low MHC class II that represent a subset of patrolling monocytes" [MGI:Annie_Speak]
Show

Allelic Composition: Memo1tm1b(EUCOMM)Wtsi/Memo1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Memo1tm1b(EUCOMM)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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