ENSMUSG00000039278


Mus musculus

Features
Gene ID: ENSMUSG00000039278
  
Biological name :Pcsk1n
  
Synonyms : Pcsk1n / ProSAAS KEP Big SAAS Little SAAS Big PEN-LEN PEN PEN-20 PEN-19 Little LEN Big LEN / Q9QXV0
  
Possible biological names infered from orthology : proprotein convertase subtilisin/kexin type 1 inhibitor / Q9UHG2
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A1.1
Gene start: 7919822
Gene end: 7924410
  
Corresponding Affymetrix probe sets: 10598493 (MoGene1.0st)   1416965_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040342
NCBI entrez gene - 30052     See in Manteia.
MGI - MGI:1353431
RefSeq - NM_013892
RefSeq Peptide - NP_038920
swissprot - Q9QXV0
Ensembl - ENSMUSG00000039278
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCSK1NENSG00000102109Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010832  ProSAAS


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002021 response to dietary excess IDA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0009409 response to cold IDA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0016486 peptide hormone processing IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0030141 secretory granule IDA
 molecular_functionGO:0004866 endopeptidase inhibitor activity IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001175 abnormal lung morphology "malformed organ of respiration" [J:35802]
Show

Allelic Composition: Padi6tm1b(KOMP)Wtsi/Padi6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Padi6tm1b(KOMP)Wtsi/Ucd

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Timd4tm1Kuch/Timd4tm1Kuch
Genetic Background: C57BL/6-Timd4tm1Kuch

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
Show

Allelic Composition: Timd4tm1Kuch/Timd4tm1Kuch
Genetic Background: C57BL/6-Timd4tm1Kuch

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Padi6tm1b(KOMP)Wtsi/Padi6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Padi6tm1b(KOMP)Wtsi/Ucd

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Timd4tm1Kuch/Timd4tm1Kuch
Genetic Background: C57BL/6-Timd4tm1Kuch

 MP:0003271 abnormal duodenum morphology "malformation in the first division of the small intestine that extends from the pyloris to the junction with the jejunum " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Padi6tm1b(KOMP)Wtsi/Padi6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Padi6tm1b(KOMP)Wtsi/Ucd

 MP:0003313 abnormal locomotor activation "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Timd4tm1Kuch/Timd4tm1Kuch
Genetic Background: C57BL/6-Timd4tm1Kuch

 MP:0003908 decreased stereotypic behavior "less frequent incidence of repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Timd4tm1Kuch/Timd4tm1Kuch
Genetic Background: C57BL/6-Timd4tm1Kuch

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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