ENSMUSG00000039546


Mus musculus

Features
Gene ID: ENSMUSG00000039546
  
Biological name :Ajap1
  
Synonyms : A2ALI5 / Adherens junction-associated protein 1 / Ajap1
  
Possible biological names infered from orthology : adherens junctions associated protein 1 / Q9UKB5
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E2
Gene start: 153373221
Gene end: 153482811
  
Corresponding Affymetrix probe sets: 10518947 (MoGene1.0st)   1438662_at (Mouse Genome 430 2.0 Array)   1456197_x_at (Mouse Genome 430 2.0 Array)   1457427_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101271
Ensembl peptide - ENSMUSP00000116651
NCBI entrez gene - 230959     See in Manteia.
MGI - MGI:2685419
RefSeq - NM_001099299
RefSeq - XM_006538824
RefSeq Peptide - NP_001092769
swissprot - D6RH95
swissprot - A2ALI5
Ensembl - ENSMUSG00000039546
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ajap1ENSDARG00000038655Danio rerio
 AJAP1ENSGALG00000027265Gallus gallus
 AJAP1ENSG00000196581Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029198  AJAP1/PANP, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001953 negative regulation of cell-matrix adhesion IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0030860 regulation of polarized epithelial cell differentiation IEA
 biological_processGO:0061045 negative regulation of wound healing IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0044214 spanning component of plasma membrane IEA
 cellular_componentGO:0044291 cell-cell contact zone IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0003795 abnormal bone structure 
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Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0005627 increased circulating potassium level "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0005633 increased circulating sodium level "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

 MP:0011396 abnormal sleep behavior "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]
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Allelic Composition: Ahrrtm1b(KOMP)Wtsi/Ahrrtm1b(KOMP)Wtsi
Genetic Background: B6N(Cg)-Ahrrtm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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