ENSMUSG00000039775


Mus musculus

Features
Gene ID: ENSMUSG00000039775
  
Biological name :Defb3
  
Synonyms : Beta-defensin 3 / Defb3 / Q9WTL0
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A1.3
Gene start: 19293360
Gene end: 19295291
  
Corresponding Affymetrix probe sets: 10570621 (MoGene1.0st)   1421806_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033852
NCBI entrez gene - 27358     See in Manteia.
MGI - MGI:1351612
RefSeq - NM_013756
RefSeq Peptide - NP_038784
swissprot - Q9WTL0
Ensembl - ENSMUSG00000039775
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Defb8ENSMUSG0000003147167
Defb4 / P82019 / Beta-defensin 4 ENSMUSG0000005923059
Defb6 / Q91VD6 / Beta-defensin 6 ENSMUSG0000005075659


Protein motifs (from Interpro)
Interpro ID Name
 IPR001855  Beta defensin type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006952 defense response IEA
 biological_processGO:0042742 defense response to bacterium IMP
 cellular_componentGO:0005576 extracellular region IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Prdm14tm1e(EUCOMM)Wtsi/Prdm14tm1e(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0001313 increased incidence of corneal inflammation "greater than average and persistent occurrence of corneal irritation" [J:4606]
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Allelic Composition: Prdm14tm1e(EUCOMM)Wtsi/Prdm14tm1e(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cd14tm1Smg/Cd14tm1Smg
Genetic Background: involves: 129S1/Sv

 MP:0005399 increased susceptibility to fungal infection "greater likelihood that an organism will develop ill effects from infection by a yeast or mold, or from components of, or toxins produced by, these organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Prdm14tm1e(EUCOMM)Wtsi/Prdm14tm1e(EUCOMM)Wtsi
Genetic Background: involves: C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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