ENSMUSG00000039873


Mus musculus

Features
Gene ID: ENSMUSG00000039873
  
Biological name :Neurl2
  
Synonyms : neuralized E3 ubiquitin protein ligase 2 / Neurl2
  
Possible biological names infered from orthology : Q9BR09
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 164830732
Gene end: 164833456
  
Corresponding Affymetrix probe sets: 10489566 (MoGene1.0st)   1429141_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041806
NCBI entrez gene - 415115     See in Manteia.
MGI - MGI:3043305
RefSeq - NM_001082974
RefSeq Peptide - NP_001076443
swissprot - A2A5J5
Ensembl - ENSMUSG00000039873
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neurl2ENSDARG00000062446Danio rerio
 NEURL2ENSGALG00000006854Gallus gallus
 NEURL2ENSG00000124257Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Neurl4 / Q5NCX5 / Neuralized-like protein 4 / Q96JN8* / neuralized E3 ubiquitin protein ligase 4*ENSMUSG0000004728427


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR006573  Neuralized homology repeat (NHR) domain
 IPR036036  SOCS box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000759 abnormal skeletal muscle morphology "anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptpn22tm2Achn/Ptpn22tm2Achn
Genetic Background: involves: C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Ptpn22tm2Achn/Ptpn22tm2Achn
Genetic Background: involves: C57BL/6

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nab2tm1b(EUCOMM)Hmgu/Nab2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nab2tm1b(EUCOMM)Hmgu/Ics

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tpp1tm1Plob/Tpp1tm1.1Plob
Genetic Background: B6.129S1-Tpp1tm1Plob/Tpp1tm1.1Plob

Allelic Composition: Neurl1atm1Ynj/Neurl1atm1Ynj,Neurl2tm1Kong/Neurl2tm1Kong
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6

 MP:0003898 abnormal QRS complex "anomaly in the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarise prior to their contraction" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nab2tm1b(EUCOMM)Hmgu/Nab2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nab2tm1b(EUCOMM)Hmgu/Ics

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nab2tm1b(EUCOMM)Hmgu/Nab2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nab2tm1b(EUCOMM)Hmgu/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr