ENSMUSG00000040205


Mus musculus

Features
Gene ID: ENSMUSG00000040205
  
Biological name :Cuzd1
  
Synonyms : CUB and zona pellucida like domains 1 / Cuzd1
  
Possible biological names infered from orthology : Q86UP6
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F3
Gene start: 131308554
Gene end: 131322292
  
Corresponding Affymetrix probe sets: 10568502 (MoGene1.0st)   1417413_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037168
NCBI entrez gene - 16433     See in Manteia.
MGI - MGI:1202881
RefSeq - NM_008411
RefSeq Peptide - NP_032437
swissprot - B2RU69
Ensembl - ENSMUSG00000040205
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cuzd1.1ENSDARG00000089050Danio rerio
 cuzd1.2ENSDARG00000025311Danio rerio
 CUZD1ENSGALG00000038254Gallus gallus
 CUZD1ENSG00000138161Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000859  CUB domain
 IPR001507  Zona pellucida domain
 IPR029834  CUB and zona pellucida-like domain-containing protein 1
 IPR035914  Spermadhesin, CUB domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000662 abnormal branching of the mammary ductal tree "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0003718 maternal effect "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004761 susceptibility to induced pancreatitis "more likely than normal to develop an inflammatory response, or an increased inflammatory response in the pancreatic tissue after experimental manipulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:hdene "Howard Dene, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdh1tm1Jjon/Cdh1+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0006270 abnormal mammary gland growth during lactation "anomaly in the final stage of mammary growth that occurs during the start of lactation" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009506 abnormal mammary gland alveolus morphology "any structural anomaly of the sac-like structure of the mammary gland that secretes milk after pregnancy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdh1tm1Jjon/Cdh1+,Trp53tm1Brn/Trp53tm1Brn,Tg(KRT14-cre)8Brn/0
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0010174 decreased mammary gland epithelium proliferation "decrease in the expansion rate of the cells of the mammary gland epithelium by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0012075 impaired mammary gland growth during pregnancy "defect in the extensive and rapid branching of the mammary ducts, expansion of mammary epithelium in the stroma between the ducts with or without abnormalities in nipple maturation in preparation for lactation" [MGI:llw2]
Show

Allelic Composition: Phc1tm1Os/Phc1tm1Os,Tg(Myh7-Phc1)#Yota/0
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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