ENSMUSG00000040412


Mus musculus

Features
Gene ID: ENSMUSG00000040412
  
Biological name :5330417C22Rik
  
Synonyms : 5330417C22Rik / A2AFS3 / Mus musculus RIKEN cDNA 5330417C22 (5330417C22Rik), transcript variant 1, mRNA.
  
Possible biological names infered from orthology : KIAA1324 / Q6UXG2
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F3
Gene start: 108455694
Gene end: 108536536
  
Corresponding Affymetrix probe sets: 10501374 (MoGene1.0st)   1427063_at (Mouse Genome 430 2.0 Array)   1442113_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138870
Ensembl peptide - ENSMUSP00000040128
Ensembl peptide - ENSMUSP00000102236
Ensembl peptide - ENSMUSP00000102237
NCBI entrez gene - 229722     See in Manteia.
MGI - MGI:1923930
RefSeq - XM_017319560
RefSeq - NM_001346518
RefSeq - XM_006501411
RefSeq - XM_006501412
RefSeq - XM_006501413
RefSeq - XM_006501414
RefSeq - XM_006501415
RefSeq - NM_001033304
RefSeq Peptide - NP_001028476
RefSeq Peptide - NP_001333447
swissprot - A2AFS3
swissprot - V9GWX1
swissprot - A0A0A0MQC6
swissprot - V9GWR8
Ensembl - ENSMUSG00000040412
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-5i3.1ENSDARG00000092762Danio rerio
 KIAA1324ENSGALG00000030941Gallus gallus
 Q6UXG2ENSG00000116299Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UZV7 / UPF0577 / 9330182L06Rik / A8MWY0* / KIAA1324L* / KIAA1324 like*ENSMUSG0000005600452


Protein motifs (from Interpro)
Interpro ID Name
 IPR009011  Mannose-6-phosphate receptor binding domain superfamily
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly ISO
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0009267 cellular response to starvation ISO
 biological_processGO:0044090 positive regulation of vacuole organization ISO
 biological_processGO:2000786 positive regulation of autophagosome assembly ISO
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome ISO
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Bmpr2tm1Mmue/Bmpr2+,Smad1tm1Rjle/Smad1+
Genetic Background: involves: 129S1/SvImJ * 129S6/SvEvTac * C57BL/6

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col1a1tm20(tetO-GFP,-cas9*D10A)Slowe/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Bmpr2tm1Mmue/Bmpr2+,Smad1tm1Rjle/Smad1+
Genetic Background: involves: 129S1/SvImJ * 129S6/SvEvTac * C57BL/6

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Bmpr2tm1Mmue/Bmpr2+,Smad1tm1Rjle/Smad1+
Genetic Background: involves: 129S1/SvImJ * 129S6/SvEvTac * C57BL/6

 MP:0002699 abnormal vitreous body "anomalies of the transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Col1a1tm20(tetO-GFP,-cas9*D10A)Slowe/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005016 decreased lymphocyte number "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Col1a1tm20(tetO-GFP,-cas9*D10A)Slowe/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Col1a1tm20(tetO-GFP,-cas9*D10A)Slowe/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
Show

Allelic Composition: Bmpr2tm1Mmue/Bmpr2+,Smad1tm1Rjle/Smad1+
Genetic Background: involves: 129S1/SvImJ * 129S6/SvEvTac * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Col1a1tm20(tetO-GFP,-cas9*D10A)Slowe/Col1a1+,Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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