ENSMUSG00000040528


Mus musculus

Features
Gene ID: ENSMUSG00000040528
  
Biological name :Milr1
  
Synonyms : Allergin-1 / Milr1 / Q3TB92
  
Possible biological names infered from orthology : mast cell immunoglobulin like receptor 1 / Q7Z6M3
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E1
Gene start: 106751226
Gene end: 106768794
  
Corresponding Affymetrix probe sets: 10382106 (MoGene1.0st)   1445687_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138617
Ensembl peptide - ENSMUSP00000138513
Ensembl peptide - ENSMUSP00000138678
Ensembl peptide - ENSMUSP00000138742
Ensembl peptide - ENSMUSP00000083538
Ensembl peptide - ENSMUSP00000102406
Ensembl peptide - ENSMUSP00000138286
Ensembl peptide - ENSMUSP00000138386
NCBI entrez gene - 380732     See in Manteia.
MGI - MGI:2685731
RefSeq - XM_017314634
RefSeq - NM_001033435
RefSeq - NM_001271372
RefSeq - NM_001271373
RefSeq - NM_001271374
RefSeq - NM_001271375
RefSeq - XM_006533648
RefSeq - XM_006533649
RefSeq - XM_011249104
RefSeq Peptide - NP_001028607
RefSeq Peptide - NP_001258302
RefSeq Peptide - NP_001258303
RefSeq Peptide - NP_001258304
RefSeq Peptide - NP_001258301
swissprot - A0A0B4J1N6
swissprot - Q3TB92
swissprot - B7ZP19
swissprot - A0A140T8Q6
swissprot - S4R1V2
Ensembl - ENSMUSG00000040528
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000046212Gallus gallus
 MILR1ENSG00000271605Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR029626  Allergin-1
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0033004 negative regulation of mast cell activation IEA
 biological_processGO:0043303 mast cell degranulation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042629 mast cell granule IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005596 increased susceptibility to type I hypersensitvity reaction "greater likelihood of developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks" [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Atcayji-hes2J/Atcayji-hes2J
Genetic Background: BALB/cJ

 MP:0008765 decreased mast cell degranulation "reduction in the exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell" [GO:0043303, MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Atcayji-hes2J/Atcayji-hes2J
Genetic Background: BALB/cJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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