ENSMUSG00000040649


Mus musculus

Features
Gene ID: ENSMUSG00000040649
  
Biological name :Rimklb
  
Synonyms : Beta-citrylglutamate synthase B / Q80WS1 / Rimklb
  
Possible biological names infered from orthology : Q9ULI2 / ribosomal modification protein rimK like family member B
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: F1
Gene start: 122447296
Gene end: 122498761
  
Corresponding Affymetrix probe sets: 10547613 (MoGene1.0st)   1429981_a_at (Mouse Genome 430 2.0 Array)   1429982_at (Mouse Genome 430 2.0 Array)   1435532_at (Mouse Genome 430 2.0 Array)   1435533_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000064467
Ensembl peptide - ENSMUSP00000144727
Ensembl peptide - ENSMUSP00000144770
Ensembl peptide - ENSMUSP00000145122
Ensembl peptide - ENSMUSP00000138104
NCBI entrez gene - 108653     See in Manteia.
MGI - MGI:1918325
RefSeq - XM_011241120
RefSeq - XM_011241116
RefSeq - XM_011241117
RefSeq - XM_011241118
RefSeq - XM_011241119
RefSeq - NM_027664
RefSeq - XM_011241115
RefSeq Peptide - NP_081940
swissprot - A0A0N4SVI6
swissprot - A0A0N4SUL3
swissprot - Q80WS1
Ensembl - ENSMUSG00000040649
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RIMKLBENSGALG00000040184Gallus gallus
 Q9ULI2ENSG00000166532Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6PFX8 / Rimkla / N-acetylaspartylglutamate synthase A / Q8IXN7* / ribosomal modification protein rimK like family member A*ENSMUSG0000004889962


Protein motifs (from Interpro)
Interpro ID Name
 IPR004666  Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX
 IPR011761  ATP-grasp fold
 IPR013651  ATP-grasp fold, RimK-type
 IPR013815  ATP-grasp fold, subdomain 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity IDA
 molecular_functionGO:0072591 citrate-L-glutamate ligase activity IDA


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

 MP:0011396 abnormal sleep behavior "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]
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Allelic Composition: Rad21ltm1b(KOMP)Wtsi/Rad21ltm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad21ltm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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