ENSMUSG00000040715


Mus musculus

Features
Gene ID: ENSMUSG00000040715
  
Biological name :Rsc1a1
  
Synonyms : Q9ER99 / Regulatory solute carrier protein family 1 member 1 / Rsc1a1
  
Possible biological names infered from orthology : Q92681 / regulator of solute carriers 1
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E1
Gene start: 141683851
Gene end: 141685599
  
Corresponding Affymetrix probe sets: 10518019 (MoGene1.0st)   1422560_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101408
NCBI entrez gene - 69994     See in Manteia.
MGI - MGI:3526447
RefSeq - NM_023544
RefSeq Peptide - NP_076033
swissprot - Q9ER99
Ensembl - ENSMUSG00000040715
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RSC1A1ENSGALG00000040663Gallus gallus
 Q92681ENSG00000215695Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
2 / Ddi2 / Q9ER99 / A2ADY9 / RSC1A1* / Q92681* / regulator of solute carriers 1*ENSMUSG00000078515100


Protein motifs (from Interpro)
Interpro ID Name
 IPR015940  Ubiquitin-associated domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0050892 intestinal absorption IMP
 biological_processGO:0051051 negative regulation of transport IBA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005903 brush border IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030054 cell junction ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008200 ion channel inhibitor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000676 abnormal water content "more or less than the normal total amount of water retained in the body" [il:Ira Lu, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0001261 obese "excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0001264 increased body size "larger than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0001669 abnormal glucose absorption "anomalous ability of the body to take in this major monosaccharide, a 6-carbon sugar" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0005448 abnormal energy balance "aberrant intake or expenditure of calories as compared to the normal state" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0005449 abnormal food intake "anomalous total number of calories taken in daily when compared to the norm" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0005458 increased percent body fat "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0005669 increased circulating leptin level "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

 MP:0006094 adipocyte hypertrophy "increase in the size of fat cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:90802]
Show

Allelic Composition: Ap3b1pe-13J/Ap3b1pe-13J
Genetic Background: STOCK Tg(CAG-EGFP)B5Nagy/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr