ENSMUSG00000040774


Mus musculus

Features
Gene ID: ENSMUSG00000040774
  
Biological name :Cept1
  
Synonyms : Cept1 / Mus musculus choline/ethanolaminephosphotransferase 1 (Cept1), transcript variant 3, mRNA. / Q8BGS7
  
Possible biological names infered from orthology : choline/ethanolamine phosphotransferase 1 / Q9Y6K0
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.3
Gene start: 106502260
Gene end: 106547802
  
Corresponding Affymetrix probe sets: 10501051 (MoGene1.0st)   1416471_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112509
Ensembl peptide - ENSMUSP00000115898
Ensembl peptide - ENSMUSP00000142097
Ensembl peptide - ENSMUSP00000122460
Ensembl peptide - ENSMUSP00000118343
Ensembl peptide - ENSMUSP00000037277
Ensembl peptide - ENSMUSP00000065743
NCBI entrez gene - 99712     See in Manteia.
MGI - MGI:2139793
RefSeq - NM_133869
RefSeq - XM_017319840
RefSeq - XM_006502472
RefSeq - XM_006502471
RefSeq - NM_001293694
RefSeq - NM_001357818
RefSeq Peptide - NP_001280623
RefSeq Peptide - NP_001344747
RefSeq Peptide - NP_001344748
RefSeq Peptide - NP_598630
swissprot - D3Z5Y5
swissprot - Q8BGS7
swissprot - D6RFR8
swissprot - A0A0A6YXR0
swissprot - D3YX12
Ensembl - ENSMUSG00000040774
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cept1aENSDARG00000058716Danio rerio
 cept1bENSDARG00000021177Danio rerio
 CEPT1ENSGALG00000000142Gallus gallus
 CEPT1ENSG00000134255Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chpt1 / Q8C025 / Cholinephosphotransferase 1 / Q8WUD6* / choline phosphotransferase 1*ENSMUSG0000006000258
Q80TA1 / Selenoi / selenoprotein I / Q9C0D9*ENSMUSG0000007570324


Protein motifs (from Interpro)
Interpro ID Name
 IPR000462  CDP-alcohol phosphatidyltransferase
 IPR014472  Choline/ethanolamine phosphotransferase
 IPR027469  Cation efflux transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006646 phosphatidylethanolamine biosynthetic process IEA
 biological_processGO:0006656 phosphatidylcholine biosynthetic process IDA
 biological_processGO:0006657 CDP-choline pathway IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0004142 diacylglycerol cholinephosphotransferase activity IEA
 molecular_functionGO:0004307 ethanolaminephosphotransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016780 phosphotransferase activity, for other substituted phosphate groups IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PC
Synthesis of PE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0002891 increased insulin sensitivity "greater ability to clear glucose from the bloodstream when given insulin than normal; can result in hypoglycemia" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0010378 increased respiratory quotient "increase in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0010954 abnormal cellular respiration "anomaly in the enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)" [GO:0045333]
Show

Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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