ENSMUSG00000040969


Mus musculus

Features
Gene ID: ENSMUSG00000040969
  
Biological name :Arhgef38
  
Synonyms : Arhgef38 / Q80VK6 / Rho guanine nucleotide exchange factor 38
  
Possible biological names infered from orthology : Q9NXL2
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: G3
Gene start: 133112278
Gene end: 133234949
  
Corresponding Affymetrix probe sets: 10502273 (MoGene1.0st)   10502279 (MoGene1.0st)   1431629_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124280
Ensembl peptide - ENSMUSP00000124776
Ensembl peptide - ENSMUSP00000054558
Ensembl peptide - ENSMUSP00000114238
NCBI entrez gene - 77669     See in Manteia.
MGI - MGI:1924919
RefSeq - NM_029953
RefSeq Peptide - NP_084229
swissprot - E0CXB4
swissprot - F6U786
swissprot - Q80VK6
Ensembl - ENSMUSG00000040969
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef38ENSDARG00000079377Danio rerio
 ENSGALG00000010577Gallus gallus
 Q9NXL2ENSG00000236699Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dnmbp / dynamin binding protein / Q6XZF7*ENSMUSG0000002519532
Arhgef37 / Rho guanine nucleotide exchange factor 37 / A1IGU5*ENSMUSG0000004509421


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001452  SH3 domain
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IBA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0005566 decreased blood urea nitrogen level "low circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr