Manteia

ENSMUSG00000041346

Mus musculus

Features

Gene ID:	ENSMUSG00000041346

Biological name :	Wrap53

Synonyms :	Q8VC51 / WD repeat containing, antisense to Trp53 / Wrap53

Possible biological names infered from orthology :	Q9BUR4 / WD repeat containing antisense to TP53

Species:	Mus musculus

Chr. number:	11
Strand:	-1
Band:	B3
Gene start:	69561758
Gene end:	69580255

Corresponding Affymetrix probe sets:	10387492 (MoGene1.0st) 1423808_at (Mouse Genome 430 2.0 Array) 1456724_x_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000047825 Ensembl peptide - ENSMUSP00000121040 NCBI entrez gene - 216853 See in Manteia. MGI - MGI:2384933 RefSeq - NM_144824 RefSeq Peptide - NP_659073 swissprot - I7HJ86 swissprot - Q8VC51 Ensembl - ENSMUSG00000041346

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR001680	WD40 repeat
IPR015943	WD40/YVTN repeat-like-containing domain superfamily
IPR017986	WD40-repeat-containing domain
IPR036322	WD40-repeat-containing domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007004	telomere maintenance via telomerase	IEA
biological_process	GO:0032203	telomere formation via telomerase	IEA
biological_process	GO:0051973	positive regulation of telomerase activity	IEA
biological_process	GO:0070200	establishment of protein localization to telomere	IEA
biological_process	GO:0090666	scaRNA localization to Cajal body	IEA
biological_process	GO:0090671	telomerase RNA localization to Cajal body	IEA
biological_process	GO:1904851	positive regulation of establishment of protein localization to telomere	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005697	telomerase holoenzyme complex	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005829	cytosol	IEA
cellular_component	GO:0015030	Cajal body	ISS
cellular_component	GO:0016604	nuclear body	IEA
molecular_function	GO:0003723	RNA binding	ISO
molecular_function	GO:0005515	protein binding	IEA
molecular_function	GO:0042802	identical protein binding	IEA
molecular_function	GO:0044877	protein-containing complex binding	IEA
molecular_function	GO:0051087	chaperone binding	IEA
molecular_function	GO:0070034	telomerase RNA binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Ube2c^{tm1.1(KOMP)Wtsi}/Ube2c⁺ Genetic Background: C57BL/6N-Ube2c^{tm1.1(KOMP)Wtsi}/J
MP:0013158	decreased KLRG1+ CD4 alpha beta T cell number	"reduction in the number of CD4+ alpha beta T cells that express KLRG1, a marker of effector/memory and regulatory T cells" [MGI:csmith]	Show Allelic Composition: Tmem79^{tm1.1(KOMP)Wtsi}/Tmem79^{tm1.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Tmem79^{tm1.1(KOMP)Wtsi}/J
MP:0013294	prenatal lethality prior to heart atrial septation	"death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]	Show Allelic Composition: Ube2c^{tm1.1(KOMP)Wtsi}/Ube2c⁺ Genetic Background: C57BL/6N-Ube2c^{tm1.1(KOMP)Wtsi}/J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr