ENSMUSG00000041801


Mus musculus

Features
Gene ID: ENSMUSG00000041801
  
Biological name :Phlda3
  
Synonyms : Phlda3 / Pleckstrin homology-like domain family A member 3 / Q9WV95
  
Possible biological names infered from orthology : Q9Y5J5
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 135766119
Gene end: 135769136
  
Corresponding Affymetrix probe sets: 10350146 (MoGene1.0st)   1449002_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040614
NCBI entrez gene - 27280     See in Manteia.
MGI - MGI:1351485
RefSeq - NM_013750
RefSeq Peptide - NP_038778
swissprot - Q9WV95
Ensembl - ENSMUSG00000041801
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PHLDA3ENSGALG00000019802Gallus gallus
 PHLDA3ENSG00000174307Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phlda1 / Q62392 / Pleckstrin homology-like domain family A member 1 / Q8WV24*ENSMUSG0000002020552
O08969 / Phlda2 / Pleckstrin homology-like domain family A member 2 / Q53GA4*ENSMUSG0000001076042


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004920 increased placenta weight "increase in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Phlda2tm1Bty/Phlda2tm1Bty,Phlda3tm1Bty/Phlda3tm1Bty
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Phlda2tm2Bty/Phlda2tm2Bty,Phlda3tm1Bty/Phlda3tm1Bty
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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