MP:0000043 | organ of Corti degeneration | "a retrogressive impairment of function or destruction of the highly specialized epithelium in the floor of the ductus cochlearis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Pgm1b-m1Ehs/Pgm1b-m1Ehs Genetic Background: involves: DBA/2J
|
MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0000186 | decreased circulating HDL cholesterol level | "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0000221 | decreased WBC count | "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Elk4tm1a(EUCOMM)Wtsi/Elk4tm1a(EUCOMM)Wtsi Genetic Background: Not Specified
|
MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Elk4tm1a(EUCOMM)Wtsi/Elk4tm1a(EUCOMM)Wtsi Genetic Background: Not Specified
|
MP:0001394 | circling | "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295] |
Show
Allelic Composition: Pgm1b-m1Ehs/Pgm1b-m1Ehs Genetic Background: involves: DBA/2J
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0001399 | hyperactivity | "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125] |
Show
Allelic Composition: Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1+ Genetic Background: C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Nju
|
MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
Show
Allelic Composition: Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1+ Genetic Background: C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Nju
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0001410 | head bobbing | "compulsive up and down movement of the head" [J:17123] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0001486 | abnormal startle reflex | "abberant threshold or reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3] |
Show
Allelic Composition: Elk4tm1a(EUCOMM)Wtsi/Elk4tm1a(EUCOMM)Wtsi Genetic Background: Not Specified
|
MP:0001489 | decreased startle reflex | "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3] |
Show
Allelic Composition: Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1+ Genetic Background: C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Nju
|
MP:0001512 | trunk curl | "posture of the trunk in a curled position" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1+ Genetic Background: C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Nju
|
MP:0001967 | deafness | "inability to hear" [J:57651] |
Show
Allelic Composition: Pgm1b-m1Ehs/Pgm1b-m1Ehs Genetic Background: involves: DBA/2J
|
MP:0002102 | abnormal ear morphology | "structural or developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ehmt1tm1b(EUCOMM)Hmgu/Ehmt1+ Genetic Background: C57BL/6N-Ehmt1tm1b(EUCOMM)Hmgu/Nju
|
MP:0002590 | increased mean corpuscular volume | "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0002644 | decreased circulating triglyceride level | "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0002764 | short tibia | " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0002857 | cochlear ganglion degeneration | "loss of neural cell bodies in the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pgm1b-m1Ehs/Pgm1b-m1Ehs Genetic Background: involves: DBA/2J
|
MP:0002874 | decreased hemoglobin content | "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0002968 | increased circulating alkaline phosphatase level | "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0003019 | increased circulating chloride level | "elevated concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0003062 | abnormal coping response | "altered ability to respond productively to a stressful situation or stimulus, or failure to seek pleasurable stimuli" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0003179 | decreased platelet count | "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0003313 | abnormal locomotor activation | "altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0003382 | straub tail | "condition in which an animal carries its tail in an erect (vertical or nearly vertical) position; often seen upon opioid and other drug treatment" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0003795 | abnormal bone structure | |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0003960 | increased lean body mass | "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0003961 | decreased lean body mass | "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0004521 | abnormal cochlear hair cell stereociliary bundle morphology | "any structural anomaly or disruption of the typical pattern of arrangement of mechanosensitive hair bundles which are composed of thick long microvilli (stereocilia) and are located at the apical end of cochlear inner and outer hair cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Pgm1b-m1Ehs/Pgm1b-m1Ehs Genetic Background: involves: DBA/2J
|
MP:0004924 | abnormal behavior | "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0004953 | decreased spleen weight | "reduction in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0005017 | decreased B cell number | "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0005179 | decreased total circulating cholesterol level | "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0005316 | abnormal response to tactile stimuli | "anomalous reflex action normally induced by touch or pain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0005560 | decreased circulating glucose level | "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0005561 | increased mean corpuscular hemoglobin | "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0005564 | increased hemoglobin content | "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0005565 | increased blood urea nitrogen level | "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0006359 | absent startle reflex | "failure to respond to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Pgm1b-m1Ehs/Pgm1b-m1Ehs Genetic Background: involves: DBA/2J
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0009142 | decreased prepulse inhibition | "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0010053 | decreased grip strength | "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
Allelic Composition: Elmod1tm1a(EUCOMM)Hmgu/Elmod1tm1a(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1a(EUCOMM)Hmgu/H
|
MP:0010124 | decreased bone mineral content | "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|
MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
Show
Allelic Composition: Pgm1b-m1Ehs/Pgm1b-m1Ehs Genetic Background: involves: DBA/2J
Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H
|