ENSMUSG00000042029


Mus musculus

Features
Gene ID: ENSMUSG00000042029
  
Biological name :Ncapg2
  
Synonyms : Ncapg2 / non-SMC condensin II complex, subunit G2 / Q6DFV1
  
Possible biological names infered from orthology : Q86XI2
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: F2
Gene start: 116405402
Gene end: 116463731
  
Corresponding Affymetrix probe sets: 10399087 (MoGene1.0st)   1417926_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152505
Ensembl peptide - ENSMUSP00000152831
Ensembl peptide - ENSMUSP00000081889
Ensembl peptide - ENSMUSP00000152384
NCBI entrez gene - 76044     See in Manteia.
MGI - MGI:1923294
RefSeq - XM_006516356
RefSeq - XM_006516351
RefSeq - XM_006516352
RefSeq - XM_006516353
RefSeq - XM_006516354
RefSeq - XM_006516355
RefSeq - NM_133762
RefSeq - XM_006516349
RefSeq - XM_006516350
RefSeq Peptide - NP_598523
swissprot - A0A1Y7VP55
swissprot - A0A1Y7VLA8
swissprot - A0A1Y7VJK1
swissprot - Q6DFV1
Ensembl - ENSMUSG00000042029
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ncapg2ENSDARG00000060023Danio rerio
 NCAPG2ENSGALG00000006525Gallus gallus
 NCAPG2ENSG00000146918Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024741  Condensin-2 complex subunit G2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001833 inner cell mass cell proliferation IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0030261 chromosome condensation IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000796 condensin complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035064 methylated histone binding IEA


Pathways (from Reactome)
Pathway description
Condensation of Prophase Chromosomes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001694 failure to form egg cylinders "inability of inner cell mass cells to grow towards the abembryonic pole to form a cylinder-like structure" [The Atlas of Mouse Development , Revised edition:ISBN 0-12-402035-6, MGI:cls, J:34458]
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Allelic Composition: Aestm1Grid/Aestm1Grid,Notch1tm1Grid/Notch1+
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0010380 inner cell mass apoptosis "the cells of the blastocyst that develop into the body of the embryo are undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Aestm1Grid/Aestm1Grid,Notch1tm1Grid/Notch1+
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
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Allelic Composition: Aestm1Grid/Aestm1Grid,Notch1tm1Grid/Notch1+
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0012114 absent inner cell mass proliferation 
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Allelic Composition: Aestm1Grid/Aestm1Grid,Notch1tm1Grid/Notch1+
Genetic Background: involves: 129S1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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