| MP:0001552 | increased circulating triglyceride level | "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0005178 | increased total circulating cholesterol level | "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0005290 | decreased oxygen consumption | "less than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0005293 | impaired glucose tolerance | "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0005534 | decreased body temperature | "less than the level of heat natural to a living being" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0005559 | increased circulating glucose level | "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0005599 | increased cardiac muscle contractility | "greater than the normal ability of the heart muscle to shorten or to develop increased tension
" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Terttm1Sear/Terttm1Sear
Genetic Background: involves: 129S4/SvJae * C57BL/6
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| MP:0005658 | susceptibility to diet-induced obesity | "more likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0008908 | increased total fat pad weight | "greater than average weight of the fat pads" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0009121 | increased white fat cell lipid droplet size | "increase in the size of the single large lipid droplet or vacuole of white fat cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0009124 | increased brown fat cell lipid droplet size | "increase in the size of the multiple small droplets of triglycerides found in brown adipocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0009763 | increased sensitivity to induced morbidity/mortality | "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0011049 | impaired adaptive thermogenesis | "inability or reduced ability to produce heat in response to short term environmental changes, such as stress, diet or reduced temperature, often resulting in metabolic inefficiency or death" [MGI:csmith, PMID:16836744] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0011940 | decreased food intake | "reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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| MP:0014142 | increased body fat mass | "increased physical bulk or volume of fat in the whole body" [MGI:csmith] |
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL
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