ENSMUSG00000042106


Mus musculus

Features
Gene ID: ENSMUSG00000042106
  
Biological name :Fam212a
  
Synonyms : Fam212a / PAK4-inhibitor INKA1 / Q9CX62
  
Possible biological names infered from orthology : family with sequence similarity 212 member A / Q96EL1
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F1
Gene start: 107984223
Gene end: 107985879
  
Corresponding Affymetrix probe sets: 10596812 (MoGene1.0st)   1452903_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040433
Ensembl peptide - ENSMUSP00000134980
NCBI entrez gene - 68176     See in Manteia.
MGI - MGI:1915426
RefSeq - NM_026597
RefSeq Peptide - NP_080873
swissprot - H3BJG7
swissprot - Q9CX62
Ensembl - ENSMUSG00000042106
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 F1QPR4ENSDARG00000070404Danio rerio
 F1QR98ENSDARG00000070360Danio rerio
 FAM212AENSGALG00000035777Gallus gallus
 Q96EL1ENSG00000185614Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80VY2 / Fam212b / PAK4-inhibitor INKA2 / Q9NTI7* / family with sequence similarity 212 member B*ENSMUSG0000004845818


Protein motifs (from Interpro)
Interpro ID Name
 IPR029267  FAM212 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0021915 neural tube development IMP
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030291 protein serine/threonine kinase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Col8a2Aca23/Col8a2Aca23
Genetic Background: C57BL/6J-Col8a2Aca23

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col8a2Aca23/Col8a2Aca23
Genetic Background: C57BL/6J-Col8a2Aca23

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Col8a2Aca23/Col8a2Aca23
Genetic Background: C57BL/6J-Col8a2Aca23

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr