ENSMUSG00000042197


Mus musculus

Features
Gene ID: ENSMUSG00000042197
  
Biological name :Zfp451
  
Synonyms : Q8C0P7 / Zfp451 / zinc finger protein 451
  
Possible biological names infered from orthology : Q9Y4E5 / ZNF451
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: B
Gene start: 33761545
Gene end: 33814595
  
Corresponding Affymetrix probe sets: 10353754 (MoGene1.0st)   1427208_at (Mouse Genome 430 2.0 Array)   1451816_at (Mouse Genome 430 2.0 Array)   1455943_at (Mouse Genome 430 2.0 Array)   1456350_at (Mouse Genome 430 2.0 Array)   1456415_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141714
Ensembl peptide - ENSMUSP00000110821
Ensembl peptide - ENSMUSP00000141813
Ensembl peptide - ENSMUSP00000137992
Ensembl peptide - ENSMUSP00000019861
Ensembl peptide - ENSMUSP00000044372
NCBI entrez gene - 98403     See in Manteia.
MGI - MGI:2137896
RefSeq - NM_133817
RefSeq - XM_017313044
RefSeq - XM_011238626
RefSeq - XM_006496370
RefSeq - NM_001290699
RefSeq - NM_001290700
RefSeq Peptide - NP_001277628
RefSeq Peptide - NP_001277629
RefSeq Peptide - NP_598578
swissprot - A0A0A6YX30
swissprot - Q8C0P7
swissprot - Q8VCL4
swissprot - A0A0A6YWV3
swissprot - E9Q9H6
swissprot - M0QWT6
Ensembl - ENSMUSG00000042197
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf451ENSDARG00000076939Danio rerio
 ZNF451ENSGALG00000016282Gallus gallus
 Q9Y4E5ENSG00000112200Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR021623  Lamina-associated polypeptide 2 alpha, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016925 protein sumoylation ISO
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:2000616 negative regulation of histone H3-K9 acetylation IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061665 SUMO ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0001944 abnormal pancreas morphology "malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0002060 abnormal skin morphology "malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr