ENSMUSG00000042410


Mus musculus

Features
Gene ID: ENSMUSG00000042410
  
Biological name :Agps
  
Synonyms : Agps / alkylglycerone phosphate synthase
  
Possible biological names infered from orthology : O00116
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C3
Gene start: 75832177
Gene end: 75931350
  
Corresponding Affymetrix probe sets: 10473024 (MoGene1.0st)   1434919_at (Mouse Genome 430 2.0 Array)   1443797_at (Mouse Genome 430 2.0 Array)   1454918_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134773
Ensembl peptide - ENSMUSP00000135457
Ensembl peptide - ENSMUSP00000134806
Ensembl peptide - ENSMUSP00000041967
Ensembl peptide - ENSMUSP00000107583
NCBI entrez gene - 228061     See in Manteia.
MGI - MGI:2443065
RefSeq - NM_172666
RefSeq Peptide - NP_766254
swissprot - H3BJ14
swissprot - A2AL50
swissprot - H3BKN2
swissprot - A2AL49
swissprot - H3BIY5
Ensembl - ENSMUSG00000042410
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agpsENSDARG00000042821Danio rerio
 AGPSENSGALG00000009236Gallus gallus
 AGPSENSG00000018510Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ldhd / Q7TNG8 / Probable D-lactate dehydrogenase, mitochondrial / Q86WU2* / lactate dehydrogenase D*ENSMUSG0000003195817


Protein motifs (from Interpro)
Interpro ID Name
 IPR004113  FAD-linked oxidase, C-terminal
 IPR006094  FAD linked oxidase, N-terminal
 IPR016164  FAD-linked oxidase-like, C-terminal
 IPR016166  FAD-binding, type 2
 IPR016167  FAD-binding, type 2, subdomain 1
 IPR016171  Vanillyl-alcohol oxidase, C-terminal subdomain 2
 IPR025650  Alkyldihydroxyacetonephosphate synthase
 IPR036318  FAD-binding, type 2-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0008610 lipid biosynthetic process IEA
 biological_processGO:0008611 ether lipid biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005777 peroxisome IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008609 alkylglycerone-phosphate synthase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA


Pathways (from Reactome)
Pathway description
Plasmalogen biosynthesis
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0001547 abnormal lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0002579 disorganized secondary lens fibers "deformation or misalignment of the elongated cells that form the crystalline lens" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:70385]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Ern1tm1Rjk/Ern1tm2.1Rjk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr