ENSMUSG00000042523


Mus musculus

Features
Gene ID: ENSMUSG00000042523
  
Biological name :Dnal1
  
Synonyms : Dnal1 / Mus musculus dynein, axonemal, light chain 1 (Dnal1), transcript variant 2, mRNA. / Q05A62
  
Possible biological names infered from orthology : dynein axonemal light chain 1 / Q4LDG9
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: D1
Gene start: 84114366
Gene end: 84147498
  
Corresponding Affymetrix probe sets: 10397179 (MoGene1.0st)   1444098_at (Mouse Genome 430 2.0 Array)   1453822_at (Mouse Genome 430 2.0 Array)   1455630_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118584
Ensembl peptide - ENSMUSP00000123497
Ensembl peptide - ENSMUSP00000121131
Ensembl peptide - ENSMUSP00000121038
Ensembl peptide - ENSMUSP00000037076
NCBI entrez gene - 105000     See in Manteia.
MGI - MGI:1921462
RefSeq - XM_006515371
RefSeq - NM_001346528
RefSeq - NM_028821
RefSeq - XM_006515370
RefSeq Peptide - NP_001333457
RefSeq Peptide - NP_083097
swissprot - D6RHN1
swissprot - D3YTL1
swissprot - D3YYU7
swissprot - Q05A62
Ensembl - ENSMUSG00000042523
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnal1ENSDARG00000034042Danio rerio
 DNAL1ENSDARG00000097505Danio rerio
 DNAL1ENSGALG00000028568Gallus gallus
 DNAL1ENSG00000119661Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0036158 outer dynein arm assembly ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0036157 outer dynein arm ISA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0043014 alpha-tubulin binding ISO
 molecular_functionGO:0045504 dynein heavy chain binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001175 abnormal lung morphology "malformed organ of respiration" [J:35802]
Show

Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0002581 abnormal ileum morphology "malformation of the portion of the small intestine that extends from the jejunum to the colon" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:70183]
Show

Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0002607 decreased basophil count "lower than average number of basophils as measured by the percent of the total number of leukocytes" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, MPD:Mouse Phenome Database]
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Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0005012 decreased eosinophil count "fewer than normal eosinophil numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0008528 polycystic kidney "the development of innumerable cysts in the kidneys filled with fluid replacing much of the mass of the kidneys leading to reduction in kidney function and frequently kidney failure" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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