ENSMUSG00000042590


Mus musculus

Features
Gene ID: ENSMUSG00000042590
  
Biological name :Ipo11
  
Synonyms : Importin-11 / Ipo11 / Q8K2V6
  
Possible biological names infered from orthology : Q9UI26
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D2.1
Gene start: 106794439
Gene end: 106936958
  
Corresponding Affymetrix probe sets: 10411974 (MoGene1.0st)   1428096_at (Mouse Genome 430 2.0 Array)   1429717_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000079667
Ensembl peptide - ENSMUSP00000140046
Ensembl peptide - ENSMUSP00000140839
NCBI entrez gene - 76582     See in Manteia.
MGI - MGI:2442377
RefSeq - XM_017315635
RefSeq - NM_029665
RefSeq - XM_006517788
RefSeq - XM_011244707
RefSeq - XM_011244708
RefSeq - XM_006517786
RefSeq - XM_006517787
RefSeq Peptide - NP_083941
swissprot - Q8K2V6
swissprot - A0A087WS00
Ensembl - ENSMUSG00000042590
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ipo11ENSDARG00000054224Danio rerio
 IPO11ENSGALG00000014740Gallus gallus
 IPO11ENSG00000086200Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001494  Importin-beta, N-terminal domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006610 ribosomal protein import into nucleus IDA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042991 obsolete transcription factor import into nucleus IBA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005635 nuclear envelope IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008536 Ran GTPase binding IEA
 molecular_functionGO:0008565 protein transporter activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004151 hypoferremia "less than the normal concentration of this metallic element in the blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Gtpbp2tm1b(KOMP)Mbp/Gtpbp2+
Genetic Background: C57BL/6N-Gtpbp2tm1b(KOMP)Mbp/Ucd

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Gtpbp2tm1b(KOMP)Mbp/Gtpbp2+
Genetic Background: C57BL/6N-Gtpbp2tm1b(KOMP)Mbp/Ucd

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Fzd4tm1.1(KOMP)Vlcg/Fzd4tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fzd4tm1.1(KOMP)Vlcg/Ucd

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Fzd4tm1.1(KOMP)Vlcg/Fzd4tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fzd4tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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