ENSMUSG00000042784


Mus musculus

Features
Gene ID: ENSMUSG00000042784
  
Biological name :Muc1
  
Synonyms : Muc1 / mucin 1, transmembrane
  
Possible biological names infered from orthology : mucin 1, cell surface associated / P15941
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 89229057
Gene end: 89233381
  
Corresponding Affymetrix probe sets: 10493474 (MoGene1.0st)   1449199_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041963
NCBI entrez gene - 17829     See in Manteia.
MGI - MGI:97231
RefSeq - NM_013605
RefSeq Peptide - NP_038633
swissprot - A0A0R4J0H1
Ensembl - ENSMUSG00000042784
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MUC1ENSG00000185499Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000082  SEA domain
 IPR036364  SEA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
O-linked glycosylation of mucins
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000505 reduced digestive secretion "decrease in the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from a cell or a gland of the digestive system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
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Allelic Composition: Nos2tm1Mrl/Nos2tm1Mrl,Tg(Myh6-Tnf)1.6Amf/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB

 MP:0000630 mammary gland hyperplasia "increased size of mammary gland due to increased cell number" [J:63229]
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Allelic Composition: Plectm5Gwi/Plectm5Gwi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lepob/Lepob
Genetic Background: involves: C57BL/6

 MP:0002647 decreased cholesterol absorption "reduced ability of the body to take in these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Grm1rcw-2J/Grm1rcw-2J
Genetic Background: either: B6(129X1)-Grm1rcw-2J/J or B6.129X1 Baxtm1Sjk/J-Grm1rcw-2J/J

 MP:0002830 gallstones "caliculi in the gallbladder or a bile duct; chemical composition of cholesterol, calcium carbonate or calcium bilirubinate" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Grm1rcw-2J/Grm1rcw-2J
Genetic Background: either: B6(129X1)-Grm1rcw-2J/J or B6.129X1 Baxtm1Sjk/J-Grm1rcw-2J/J

 MP:0003447 reduced tumor growth/size "less than expected development of tumorous growth when compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65383]
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Allelic Composition: Grm1rcw-2J/Grm1rcw-2J
Genetic Background: either: B6(129X1)-Grm1rcw-2J/J or B6.129X1 Baxtm1Sjk/J-Grm1rcw-2J/J

Allelic Composition: Muc1tm1Gend/Muc1tm1Gend,Tg(Wnt1)1Hev/?
Genetic Background: involves: FVB

 MP:0005085 abnormal gall bladder physiology "anomalous action or function of the organ that stores and concentrates bile " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Grm1rcw-2J/Grm1rcw-2J
Genetic Background: either: B6(129X1)-Grm1rcw-2J/J or B6.129X1 Baxtm1Sjk/J-Grm1rcw-2J/J

 MP:0005342 abnormal lipid absorption "anomalous ability of the body to take in fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
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Allelic Composition: Grm1rcw-2J/Grm1rcw-2J
Genetic Background: either: B6(129X1)-Grm1rcw-2J/J or B6.129X1 Baxtm1Sjk/J-Grm1rcw-2J/J

 MP:0010299 increased mammary gland tumor incidence "greater than the expected number of neoplasms in the mammary gland, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plectm5Gwi/Plectm5Gwi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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