ENSMUSG00000042918


Mus musculus

Features
Gene ID: ENSMUSG00000042918
  
Biological name :Mamstr
  
Synonyms : Mamstr / MEF2-activating motif and SAP domain-containing transcriptional regulator / Q0ZCJ7
  
Possible biological names infered from orthology : Q6ZN01
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 45639977
Gene end: 45646521
  
Corresponding Affymetrix probe sets: 10553057 (MoGene1.0st)   1431836_x_at (Mouse Genome 430 2.0 Array)   1437739_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114686
Ensembl peptide - ENSMUSP00000147269
NCBI entrez gene - 74490     See in Manteia.
MGI - MGI:1921740
RefSeq - XM_006541235
RefSeq - NM_172418
RefSeq - XM_006541232
RefSeq - XM_006541233
RefSeq - XM_006541234
RefSeq Peptide - NP_766006
swissprot - Q0ZCJ7
swissprot - A0A1B0GQV8
Ensembl - ENSMUSG00000042918
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAMSTRENSG00000176909Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR036361  SAP domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010831 positive regulation of myotube differentiation IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IPI
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Lysttm1b(EUCOMM)Wtsi/Lysttm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Lysttm1b(EUCOMM)Wtsi/Tcp

 MP:0000749 muscle degeneration "pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Dmdmdx/Dmdmdx,Mamstrtm1.2Eno/Mamstrtm1.2Eno
Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Dmdmdx/Dmdmdx,Mamstrtm1.2Eno/Mamstrtm1.2Eno
Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn

Allelic Composition: Mamstrtm1.2Eno/Mamstrtm1.2Eno,Mkl1tm1Eno/Mkl1tm1Eno
Genetic Background: involves: 129 * C57BL/6

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dmdmdx/Dmdmdx,Mamstrtm1.2Eno/Mamstrtm1.2Eno
Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn

 MP:0002269 muscular atrophy "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Mamstrtm1.2Eno/Mamstrtm1.2Eno,Mkl1tm1Eno/Mkl1tm1Eno
Genetic Background: involves: 129 * C57BL/6

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Lysttm1b(EUCOMM)Wtsi/Lysttm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Lysttm1b(EUCOMM)Wtsi/Tcp

 MP:0003795 abnormal bone structure 
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Allelic Composition: Lysttm1b(EUCOMM)Wtsi/Lysttm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Lysttm1b(EUCOMM)Wtsi/Tcp

 MP:0005150 cachexia "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Mamstrtm1.2Eno/Mamstrtm1.2Eno,Mkl1tm1Eno/Mkl1tm1Eno
Genetic Background: involves: 129 * C57BL/6

 MP:0009410 abnormal skeletal muscle satellite cell proliferation "anomaly in the ability of unfused cells in skeltal muscle to undergo expansion by cell division, usually triggered by injury or disease" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dmdmdx/Dmdmdx,Mamstrtm1.2Eno/Mamstrtm1.2Eno
Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn

Allelic Composition: Mamstrtm1.2Eno/Mamstrtm1.2Eno,Mkl1tm1Eno/Mkl1tm1Eno
Genetic Background: involves: 129 * C57BL/6

 MP:0009419 skeletal muscle fibrosis "formation of fibrous tissue within skeletal muscle as a result of repair or a reactive process" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Dmdmdx/Dmdmdx,Mamstrtm1.2Eno/Mamstrtm1.2Eno
Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lysttm1b(EUCOMM)Wtsi/Lysttm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Lysttm1b(EUCOMM)Wtsi/Tcp

 MP:0010239 decreased skeletal muscle weight "less than average skeletal muscle weight" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dmdmdx/Dmdmdx,Mamstrtm1.2Eno/Mamstrtm1.2Eno
Genetic Background: involves: 129 * C57BL/6 * C57BL/10ScSn

Allelic Composition: Mamstrtm1.2Eno/Mamstrtm1.2Eno,Mkl1tm1Eno/Mkl1tm1Eno
Genetic Background: involves: 129 * C57BL/6

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Mamstrtm1.2Eno/Mamstrtm1.2Eno,Mkl1tm1Eno/Mkl1tm1Eno
Genetic Background: involves: 129 * C57BL/6

 MP:0013239 impaired skeletal muscle regeneration "reduced ability to repair skeletal muscle after injury or disease" [MGI:csmith]
Show

Allelic Composition: Fbn1tm3.2Lysa/Fbn1+
Genetic Background: Not Specified

Allelic Composition: Mamstrtm1.2Eno/Mamstrtm1.2Eno,Mkl1tm1Eno/Mkl1tm1Eno
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Mamstrtm1.1Eno/Mamstrtm1.1Eno,Pax7tm2.1(cre/ERT2)Fan/Pax7+
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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