ENSMUSG00000042993


Mus musculus

Features
Gene ID: ENSMUSG00000042993
  
Biological name :Ifnk
  
Synonyms : Ifnk / Interferon kappa / Q7TSL0
  
Possible biological names infered from orthology : Q9P0W0
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 35152056
Gene end: 35154005
  
Corresponding Affymetrix probe sets: 10503952 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000054273
NCBI entrez gene - 387510     See in Manteia.
MGI - MGI:2683287
RefSeq - NM_199157
RefSeq Peptide - NP_954608
swissprot - Q4FZL7
swissprot - Q7TSL0
Ensembl - ENSMUSG00000042993
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000015062Gallus gallus
 IFNKENSG00000147896Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ifna1 / P01572 / Interferon alpha-1 / IFNA2* / IFNA5* / IFNA4* / IFNA6* / IFNA7* / IFNA8* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566...ENSMUSG0000009549826
Ifna14 / IFNA6* / IFNA7* / IFNA8* / IFNA2* / IFNA4* / IFNA1* / IFNA5* / P32881* / IFNA10* / IFNA13* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000009589626
Ifna7 / IFNA5* / IFNA6* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000010071325
Ifna12 / Q80SS5 / Interferon alpha-12 / IFNA2* / IFNA1* / IFNA5* / IFNA4* / IFNA6* / IFNA7* / IFNA8* / P01571* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P0156...ENSMUSG0000007381125
Ifna9 / P09235 / Interferon alpha-9 / IFNA1* / IFNA4* / IFNA6* / IFNA5* / IFNA7* / IFNA8* / IFNA2* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563*...ENSMUSG0000009527025
Ifna6 / IFNA5* / IFNA7* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000010125225
Q80SU4 / Ifna13 / Interferon alpha-13 / IFNA7* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / IFNA6* / IFNA5* / IFNA10* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P0156...ENSMUSG0000006337624
Ifna16 / IFNA6* / IFNA7* / IFNA4* / IFNA1* / IFNA2* / IFNA8* / IFNA5* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000007835524
Ifna2 / interferon alpha 2 / IFNA7* / IFNA8* / IFNA4* / IFNA1* / IFNA5* / IFNA6* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567...ENSMUSG0000007835424
Ifna5 / IFNA6* / IFNA7* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* / P01569*...ENSMUSG0000009668224
Ifna15 / IFNA5* / IFNA6* / IFNA7* / IFNA8* / IFNA1* / IFNA2* / IFNA4* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568*...ENSMUSG0000009601124
Ifna11 / Q61716 / Interferon alpha-11 / IFNA2* / IFNA1* / IFNA5* / IFNA4* / IFNA6* / IFNA7* / IFNA8* / P01571* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P0156...ENSMUSG0000010054924
Ifnab / IFNA6* / IFNA7* / IFNA8* / IFNA2* / IFNA4* / IFNA1* / IFNA5* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566* / P01567* / P01568* ...ENSMUSG0000010007924
Ifna4 / P07351 / Interferon alpha-4 / IFNA7* / IFNA5* / IFNA8* / IFNA2* / IFNA1* / IFNA6* / P32881* / IFNA10* / IFNA13* / IFNA14* / IFNA16* / IFNA17* / IFNA21* / P01562* / P01563* / P01566...ENSMUSG0000007090422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000471  Interferon alpha/beta/delta
 IPR009079  Four-helical cytokine-like, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IBA
 biological_processGO:0002286 T cell activation involved in immune response IBA
 biological_processGO:0002323 natural killer cell activation involved in immune response IBA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006959 humoral immune response IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway ISO
 biological_processGO:0030183 B cell differentiation IBA
 biological_processGO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein IBA
 biological_processGO:0042100 B cell proliferation IBA
 biological_processGO:0043330 response to exogenous dsRNA IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005126 cytokine receptor binding IEA
 molecular_functionGO:0005132 type I interferon receptor binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Grin2btm1e.1(KOMP)Wtsi/Grin2b+
Genetic Background: C57BL/6N-Grin2btm1e.1(KOMP)Wtsi/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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