ENSMUSG00000043061


Mus musculus

Features
Gene ID: ENSMUSG00000043061
  
Biological name :Tmem18
  
Synonyms : Q3TUD9 / Tmem18 / Transmembrane protein 18
  
Possible biological names infered from orthology : Q96B42
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: A2
Gene start: 30584426
Gene end: 30591215
  
Corresponding Affymetrix probe sets: 10395129 (MoGene1.0st)   1454836_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050729
NCBI entrez gene - 211986     See in Manteia.
MGI - MGI:2387176
RefSeq - NM_172049
RefSeq Peptide - NP_742046
swissprot - Q3TUD9
Ensembl - ENSMUSG00000043061
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q641M3ENSDARG00000036704Danio rerio
 Q5F410ENSGALG00000028744Gallus gallus
 Q96B42ENSG00000151353Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026721  Transmembrane protein 18


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0016477 cell migration IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0004889 increased energy expenditure "increase in the number of calories used per unit time or decrease in weight gain for a given amount of food eaten" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0005658 susceptibility to diet-induced obesity "more likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0009285 increased gonadal fat pad weight "greater than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0011939 increased food intake "increase in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0014142 increased body fat mass "increased physical bulk or volume of fat in the whole body" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0014170 increased brown adipose tissue mass "increased physical bulk or volume of brown adipose tissue" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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