ENSMUSG00000043110


Mus musculus

Features
Gene ID: ENSMUSG00000043110
  
Biological name :Lrrn4
  
Synonyms : Leucine-rich repeat neuronal protein 4 / Lrrn4 / P59383
  
Possible biological names infered from orthology : leucine rich repeat neuronal 4 / Q8WUT4
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F2
Gene start: 132868305
Gene end: 132880891
  
Corresponding Affymetrix probe sets: 10487987 (MoGene1.0st)   1435648_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057005
NCBI entrez gene - 320974     See in Manteia.
MGI - MGI:2445154
RefSeq - NM_177303
RefSeq - XM_011239602
RefSeq Peptide - NP_796277
swissprot - P59383
Ensembl - ENSMUSG00000043110
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU984579.1ENSDARG00000116863Danio rerio
 si:ch1073-303k11.2ENSDARG00000088247Danio rerio
 LRRN4ENSGALG00000008815Gallus gallus
 LRRN4ENSG00000125872Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3TYX2 / Lrrn4cl / LRRN4 C-terminal-like protein / Q8ND94* / LRRN4 C-terminal like*ENSMUSG000000716569


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007616 long-term memory IMP
 biological_processGO:0008542 visual learning IMP
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Lepob/Lepob
Genetic Background: BTBR.Cg-Lepob/WiscJ

 MP:0009454 impaired contextual conditioning "decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Lepob/Lepob
Genetic Background: BTBR.Cg-Lepob/WiscJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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