ENSMUSG00000043257


Mus musculus

Features
Gene ID: ENSMUSG00000043257
  
Biological name :Pigv
  
Synonyms : GPI mannosyltransferase 2 / Pigv / Q7TPN3
  
Possible biological names infered from orthology : phosphatidylinositol glycan anchor biosynthesis class V / Q9NUD9
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.3
Gene start: 133660387
Gene end: 133672647
  
Corresponding Affymetrix probe sets: 10517083 (MoGene1.0st)   1437663_at (Mouse Genome 430 2.0 Array)   1455075_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050647
Ensembl peptide - ENSMUSP00000065601
NCBI entrez gene - 230801     See in Manteia.
MGI - MGI:2442480
RefSeq - XM_006538747
RefSeq - NM_001145955
RefSeq - NM_001145956
RefSeq - NM_178698
RefSeq Peptide - NP_001139428
RefSeq Peptide - NP_001343395
RefSeq Peptide - NP_848813
RefSeq Peptide - NP_001139427
swissprot - Q7TPN3
Ensembl - ENSMUSG00000043257
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pigvENSDARG00000101952Danio rerio
 PIGVENSGALG00000039883Gallus gallus
 PIGVENSG00000060642Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007315  GPI mannosyltransferase 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006506 GPI anchor biosynthetic process IBA
 biological_processGO:0097502 mannosylation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031501 mannosyltransferase complex IBA
 molecular_functionGO:0000030 mannosyltransferase activity ISO
 molecular_functionGO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Synthesis of glycosylphosphatidylinositol (GPI)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0000273 overriding aorta "congenitally mispositioned aorta where the origin straddles the ventral septum and so receives ejected blood from the right ventricle as well as the left." [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:67826]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0001823 thymus hypoplasia "small size due to reduced cell number in the thymus" [J:23255]
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Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0002639 micrognathia "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0003675 kidney cysts "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0004158 right aortic arch "the aortic arch lies to the right of the trachea and esophagus; results from persistance of the entire right dorsal arch and involution of a segment of the left arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0010466 vascular ring "the trachea and esophagus are completely encircled by connected segments of the aortic arch and its branches" [http://emedicine.medscape.com]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

 MP:0011667 double outlet right ventricle with atrioventricular septal defect "a form of DORV in which there is also a complete atrioventricular canal" [MGI:csmith]
Show

Allelic Composition: Krastm3Bbd/Krastm3Bbd
Genetic Background: B6.129-Krastm3Bbd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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