ENSMUSG00000043441


Mus musculus

Features
Gene ID: ENSMUSG00000043441
  
Biological name :Gpr149
  
Synonyms : Gpr149 / G protein-coupled receptor 149 / Q3UVY1
  
Possible biological names infered from orthology : Q86SP6
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: E1
Gene start: 62529077
Gene end: 62605140
  
Corresponding Affymetrix probe sets: 10498441 (MoGene1.0st)   1438210_at (Mouse Genome 430 2.0 Array)   1456858_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000060893
NCBI entrez gene - 229357     See in Manteia.
MGI - MGI:2443628
RefSeq - XM_011240076
RefSeq - NM_177346
RefSeq - XM_006501322
RefSeq Peptide - NP_796320
swissprot - Q3UVY1
Ensembl - ENSMUSG00000043441
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPR149ENSGALG00000010337Gallus gallus
 GPR149ENSG00000174948Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001546 preantral ovarian follicle growth IMP
 biological_processGO:0001547 antral ovarian follicle growth IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IBA
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0060280 negative regulation of ovulation IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043005 neuron projection IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0042923 neuropeptide binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001130 abnormal ovarian folliculogenesis "atypical formation or failure to form the spherical ovum in the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:35782]
Show

Allelic Composition: Nlrp3m1Btlr/Nlrp3m1Btlr
Genetic Background: C57BL/6J-Nlrp3m1Btlr

 MP:0001927 abnormal oestrous cycle (sensu Rodentia) "failure of or aberrant timing of the sexual cycle of female animals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Nlrp3m1Btlr/Nlrp3m1Btlr
Genetic Background: C57BL/6J-Nlrp3m1Btlr

 MP:0001928 abnormal ovulation "aberration in the release of an ovum from a rupturing Graafin follicle, normally regulated by a surge in lutenizing hormone" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nlrp3m1Btlr/Nlrp3m1Btlr
Genetic Background: C57BL/6J-Nlrp3m1Btlr

Allelic Composition: Gpr149tm1.1Zuk/Gpr149+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * FVB/N

 MP:0001934 increased litter size "greater numbers of live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nlrp3m1Btlr/Nlrp3m1Btlr
Genetic Background: C57BL/6J-Nlrp3m1Btlr

 MP:0001968 abnormal touch/ nociception "change in the ability to sense contact with objects or in the ability to sense pain, most often registered by mechanoreceptors in the skin and mucous membranes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nmnat2Tn(sb-Tyr)2172.P9KK4BOve/Nmnat2Tn(sb-Tyr)2172.P9KK4BOve
Genetic Background: involves: FVB/N

 MP:0002161 abnormal fertility/fecundity "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nlrp3m1Btlr/Nlrp3m1Btlr
Genetic Background: C57BL/6J-Nlrp3m1Btlr

 MP:0005410 abnormal fertilization "anomaly in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nlrp3m1Btlr/Nlrp3m1Btlr
Genetic Background: C57BL/6J-Nlrp3m1Btlr

 MP:0008870 increased mature ovarian follicle number "than normal numbers of spheroid cell aggregations in the ovary containing the ovum" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Nlrp3m1Btlr/Nlrp3m1Btlr
Genetic Background: C57BL/6J-Nlrp3m1Btlr

 MP:0009017 prolonged estrus "increase in the length of the estrous phase of the estrous cycle in female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nlrp3m1Btlr/Nlrp3m1Btlr
Genetic Background: C57BL/6J-Nlrp3m1Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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