ENSMUSG00000043587


Mus musculus

Features
Gene ID: ENSMUSG00000043587
  
Biological name :Pxylp1
  
Synonyms : 2-phosphoxylose phosphatase 1 / Pxylp1 / Q8BHA9
  
Possible biological names infered from orthology : Q8TE99
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E3.3
Gene start: 96823336
Gene end: 96892669
  
Corresponding Affymetrix probe sets: 10595840 (MoGene1.0st)   1429390_at (Mouse Genome 430 2.0 Array)   1429391_at (Mouse Genome 430 2.0 Array)   1456735_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113210
Ensembl peptide - ENSMUSP00000113489
Ensembl peptide - ENSMUSP00000121537
Ensembl peptide - ENSMUSP00000120377
Ensembl peptide - ENSMUSP00000114946
Ensembl peptide - ENSMUSP00000077571
Ensembl peptide - ENSMUSP00000108574
Ensembl peptide - ENSMUSP00000113059
NCBI entrez gene - 235534     See in Manteia.
MGI - MGI:2442444
RefSeq - NM_153420
RefSeq - XM_017313346
RefSeq - XM_006511139
RefSeq - XM_006511138
RefSeq - NM_001289645
RefSeq - NM_001289646
RefSeq - NM_001289647
RefSeq Peptide - NP_001276574
RefSeq Peptide - NP_001276575
RefSeq Peptide - NP_001276576
RefSeq Peptide - NP_700469
swissprot - D3Z2N0
swissprot - Q8BHA9
swissprot - D3Z7C3
swissprot - D3YUT4
swissprot - D3YZM5
Ensembl - ENSMUSG00000043587
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pxylp1ENSDARG00000040644Danio rerio
 PXYLP1ENSGALG00000029102Gallus gallus
 PXYLP1ENSG00000155893Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000560  Histidine phosphatase superfamily, clade-2
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006024 glycosaminoglycan biosynthetic process ISS
 biological_processGO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process ISO
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0050650 chondroitin sulfate proteoglycan biosynthetic process ISS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

 MP:0005562 decreased mean corpuscular hemoglobin "less than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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