ENSMUSG00000044461


Mus musculus

Features
Gene ID: ENSMUSG00000044461
  
Biological name :Shisa2
  
Synonyms : Q8QZV2 / Shisa2 / shisa family member 2
  
Possible biological names infered from orthology : Q6UWI4
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C3
Gene start: 59625308
Gene end: 59631660
  
Corresponding Affymetrix probe sets: 10415693 (MoGene1.0st)   1423851_a_at (Mouse Genome 430 2.0 Array)   1423852_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000059391
NCBI entrez gene - 219134     See in Manteia.
MGI - MGI:2444716
RefSeq - NM_145463
RefSeq Peptide - NP_663438
swissprot - Q8QZV2
Ensembl - ENSMUSG00000044461
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 shisa2bENSDARG00000088232Danio rerio
 SHISA2ENSGALG00000043035Gallus gallus
 Q6UWI4ENSG00000180730Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UPR0 / Shisa3 / shisa family member 3 / A0PJX4*ENSMUSG0000005001040


Protein motifs (from Interpro)
Interpro ID Name
 IPR026910  Shisa family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IDA
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000837 abnormal hypothalamus morphology "any malformation or absence of the ventral part of the diencephalon extending from the region of the optic chiasm to the caudal border of the mammillary bodies and forming the inferior and lateral walls of the third ventricle; this region regulates the autonomic nervous system via hormone production and release" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Meox2tm1(cre)Sor/Meox2+,Snai1tm1Grid/Snai1tm2Grid
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Meox2tm1(cre)Sor/Meox2+,Snai1tm1Grid/Snai1tm2Grid
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor

 MP:0008974 proportional dwarf "abnormally undersized with both limbs and trunk symmetrically shorter; usually due to chemical, endocrine, nutritional or nonosseous influences" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Meox2tm1(cre)Sor/Meox2+,Snai1tm1Grid/Snai1tm2Grid
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Meox2tm1(cre)Sor/Meox2+,Snai1tm1Grid/Snai1tm2Grid
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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