ENSMUSG00000044573


Mus musculus

Features
Gene ID: ENSMUSG00000044573
  
Biological name :Acp1
  
Synonyms : acid phosphatase 1, soluble / Acp1 / Q9D358
  
Possible biological names infered from orthology : acid phosphatase 1 / P24666
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: A2
Gene start: 30893326
Gene end: 30911589
  
Corresponding Affymetrix probe sets: 10355401 (MoGene1.0st)   10399820 (MoGene1.0st)   10491883 (MoGene1.0st)   10557199 (MoGene1.0st)   10606532 (MoGene1.0st)   1422715_s_at (Mouse Genome 430 2.0 Array)   1422716_a_at (Mouse Genome 430 2.0 Array)   1422717_at (Mouse Genome 430 2.0 Array)   1449604_at (Mouse Genome 430 2.0 Array)   1450720_at (Mouse Genome 430 2.0 Array)   1450721_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073686
Ensembl peptide - ENSMUSP00000106509
Ensembl peptide - ENSMUSP00000151833
NCBI entrez gene - 11431     See in Manteia.
MGI - MGI:87881
RefSeq - NM_001110239
RefSeq - NM_021330
RefSeq Peptide - NP_001103709
RefSeq Peptide - NP_067305
swissprot - Q9D358
swissprot - Q4VAI2
swissprot - Q561M1
swissprot - A0A1W2P7X3
Ensembl - ENSMUSG00000044573
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acp1ENSDARG00000076486Danio rerio
 ACP1ENSGALG00000016363Gallus gallus
 ACP1ENSG00000143727Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002115  Protein-tyrosine phosphatase, low molecular weight, mammalian
 IPR017867  Protein-tyrosine phosphatase, low molecular weight
 IPR023485  Phosphotyrosine protein phosphatase I
 IPR036196  Phosphotyrosine protein phosphatase I superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0042383 sarcolemma IDA
 molecular_functionGO:0003993 acid phosphatase activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0004726 non-membrane spanning protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Jak1tm1.1Kuw/Jak1tm1.1Kuw
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

 MP:0003223 decreased cardiomyocyte apoptosis "decrease in the number of cardiac muscle cells undergoing programmed cell death" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Jak1tm1.1Kuw/Jak1tm1.1Kuw
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB

 MP:0004486 decreased response of heart to induced stress "decrease in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Jak1tm1.1Kuw/Jak1tm1.1Kuw
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB

 MP:0008705 increased interleukin-6 secretion "increase in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506]
Show

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

 MP:0011703 increased fibroblast proliferation "greater the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
Show

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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