ENSMUSG00000045763


Mus musculus

Features
Gene ID: ENSMUSG00000045763
  
Biological name :Basp1
  
Synonyms : Basp1 / Brain acid soluble protein 1 / Q91XV3
  
Possible biological names infered from orthology : brain abundant membrane attached signal protein 1 / P80723
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: B1
Gene start: 25363277
Gene end: 25413764
  
Corresponding Affymetrix probe sets: 10427895 (MoGene1.0st)   1428572_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053943
Ensembl peptide - ENSMUSP00000154675
NCBI entrez gene - 70350     See in Manteia.
MGI - MGI:1917600
RefSeq - NM_027395
RefSeq Peptide - NP_081671
swissprot - Q91XV3
Ensembl - ENSMUSG00000045763
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BASP1ENSGALG00000012952Gallus gallus
 BASP1ENSG00000176788Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008408  Brain acid soluble protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0072112 glomerular visceral epithelial cell differentiation IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0008180 COP9 signalosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

Allelic Composition: Basp1tm2(Gap43)Crni/Basp1tm2(Gap43)Crni
Genetic Background: Not Specified

 MP:0001106 abnormal Schwann cell "malformed or absent cells which form the insulating myelin sheaths of peripheral axons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0003651 abnormal axon outgrowth "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0004243 abnormal motor nerve terminal sprouting "aberrant response of a motor neuron to form new neuritic processes (sprouts) that emerge from the nodes of Ranvier or terminal arborizations in response to nerve injury (such as denervation), application of nerve toxin, or muscle inactivity (usually due to disease)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

Allelic Composition: Basp1tm2(Gap43)Crni/Basp1tm2(Gap43)Crni
Genetic Background: Not Specified

 MP:0005404 abnormal axon morphology "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0008415 abnormal neurite morphology "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

 MP:0011380 enlarged brain ventricle "increased size of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord" [MGI:smb]
Show

Allelic Composition: Sptbn4qv-4J/Sptbn4qv-4J
Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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