ENSMUSG00000045826


Mus musculus

Features
Gene ID: ENSMUSG00000045826
  
Biological name :Ptprcap
  
Synonyms : protein tyrosine phosphatase, receptor type, C polypeptide-associated protein / Ptprcap / Q64697
  
Possible biological names infered from orthology : protein tyrosine phosphatase, receptor type C associated protein / Q14761
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 4154606
Gene end: 4156751
  
Corresponding Affymetrix probe sets: 10460371 (MoGene1.0st)   1448511_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053412
NCBI entrez gene - 19265     See in Manteia.
MGI - MGI:97811
RefSeq - NM_016933
RefSeq Peptide - NP_058629
swissprot - Q542J3
swissprot - Q64697
Ensembl - ENSMUSG00000045826
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q14761ENSG00000213402Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR016553  Protein tyrosine phosphatase receptor type C-associated protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006952 defense response IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000688 lymphoid hyperplasia "increased cell number in lymphatic tissues" [J:62478]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak
Genetic Background: SJL.129S2(B6)-Cd8atm1Mak/Rdgz

 MP:0000702 enlarged lymph nodes "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak
Genetic Background: SJL.129S2(B6)-Cd8atm1Mak/Rdgz

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mybtm1Cgn/Mybtm1Cgn,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

 MP:0005078 abnormal cytotoxic T cell physiology "impaired function of the subset of CD8+ T lymphocytes capable of directly killing appropriately targeted cells " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tyrobptm1.1Viv/Tyrobptm1.1Viv
Genetic Background: B6.129P2-Tyrobptm1.1Viv

 MP:0005093 impaired B cell proliferation "absent or reduced ability of B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tyrobptm1.1Viv/Tyrobptm1.1Viv
Genetic Background: B6.129P2-Tyrobptm1.1Viv

 MP:0005095 decreased T cell proliferation "reduced clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Tyrobptm1.1Viv/Tyrobptm1.1Viv
Genetic Background: B6.129P2-Tyrobptm1.1Viv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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