ENSMUSG00000045996


Mus musculus

Features
Gene ID: ENSMUSG00000045996
  
Biological name :Polr2k
  
Synonyms : Polr2k / polymerase (RNA) II (DNA directed) polypeptide K / Q63871
  
Possible biological names infered from orthology : P53803 / RNA polymerase II subunit K
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: B3.1
Gene start: 36174010
Gene end: 36177010
  
Corresponding Affymetrix probe sets: 10423742 (MoGene1.0st)   10599346 (MoGene1.0st)   1452596_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000051968
Ensembl peptide - ENSMUSP00000136975
NCBI entrez gene - 17749     See in Manteia.
MGI - MGI:102725
RefSeq - NM_023127
RefSeq - NM_001039368
RefSeq Peptide - NP_001034457
RefSeq Peptide - NP_075616
swissprot - Q545V5
swissprot - Q63871
swissprot - Q8BFX0
Ensembl - ENSMUSG00000045996
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr2kENSDARG00000075616Danio rerio
 POLR2KENSGALG00000036019Gallus gallus
 P53803ENSG00000147669Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006591  RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4
 IPR029040  RNA polymerase subunit RPABC4/transcription elongation factor Spt4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006360 transcription by RNA polymerase I IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex IBA
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex IBA
 cellular_componentGO:0005736 DNA-directed RNA polymerase I complex IBA
 molecular_functionGO:0001054 RNA polymerase I activity IBA
 molecular_functionGO:0001055 RNA polymerase II activity IBA
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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