ENSMUSG00000046010


Mus musculus

Features
Gene ID: ENSMUSG00000046010
  
Biological name :Zfp830
  
Synonyms : Q8R1N0 / Zfp830 / zinc finger protein 830
  
Possible biological names infered from orthology : Q96NB3 / ZNF830
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: C
Gene start: 82764345
Gene end: 82765935
  
Corresponding Affymetrix probe sets: 1423338_at (Mouse Genome 430 2.0 Array)   1423339_s_at (Mouse Genome 430 2.0 Array)   1447932_at (Mouse Genome 430 2.0 Array)   1450942_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056154
NCBI entrez gene - 66983     See in Manteia.
MGI - MGI:1914233
RefSeq - NM_025884
RefSeq Peptide - NP_080160
swissprot - Q8R1N0
Ensembl - ENSMUSG00000046010
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000013156Gallus gallus
 Q96NB3ENSG00000198783Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003604  Matrin/U1-C-like, C2H2-type zinc finger
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001546 preantral ovarian follicle growth IMP
 biological_processGO:0001832 blastocyst growth IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0033260 nuclear DNA replication IMP
 biological_processGO:0033314 mitotic DNA replication checkpoint IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0044773 mitotic DNA damage checkpoint IMP
 biological_processGO:0048478 replication fork protection IMP
 biological_processGO:0051276 chromosome organization IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060729 intestinal epithelial structure maintenance IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Zfp830tm2.2Cota/Zfp830tm2.2Cota
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas * C57BL/6) or (involves: 129/Sv * 129S2/SvPas * BALB/c * C57BL/6)

 MP:0001728 failure of implantation "inability of the blastocyst to attach to the endometrium of the uterus" [J:38772]
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxp3tm1(CD2/CD52)Shori/Foxp3tm1(CD2/CD52)Shori
Genetic Background: involves: C57BL/6

 MP:0002718 abnormal inner cell mass "malformed or absent cells of the blastocyst that develop into the body of the embryo" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

 MP:0003077 abnormal cell cycle "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

 MP:0003694 failure to hatch from the zona pellucida "the embryo fails to break out of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, may be seen in vivo or in cultured embryos" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

 MP:0005028 abnormal trophectoderm "malformed outermost layer of cells in the blastodermic vesicle, which will contact the endometrium and take part in establishing the embryo s means of nutrition" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

 MP:0008008 early cellular replicative senescence "increase in the progression of the process in which a cell progresses from its inception to the end of its lifespan, which occurs as the cell continues cycles of growth and division" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Zfp830tm2.1Cota/Zfp830tm2.2Cota,Gt(ROSA)26Sortm2(cre/ERT2)Brn/?
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6

 MP:0011093 complete embryonic lethality at implantation "death of all organisms of a given genotype in a population at the point of implantation (Mus: E4.5)" [MGI:csmith]
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Foxp3tm1(CD2/CD52)Shori/Foxp3tm1(CD2/CD52)Shori
Genetic Background: involves: C57BL/6

Allelic Composition: Zfp830tm2.2Cota/Zfp830tm2.2Cota
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas * C57BL/6) or (involves: 129/Sv * 129S2/SvPas * BALB/c * C57BL/6)

 MP:0012113 decreased inner cell mass proliferation 
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

 MP:0012114 absent inner cell mass proliferation 
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

 MP:0012118 absent trophectoderm cell proliferation 
Show

Allelic Composition: Polgtm1Prol/Polgtm1Prol
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * ICR

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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