ENSMUSG00000046323


Mus musculus

Features
Gene ID: ENSMUSG00000046323
  
Biological name :Dppa3
  
Synonyms : Developmental pluripotency-associated protein 3 / Dppa3 / Q8QZY3
  
Possible biological names infered from orthology : developmental pluripotency associated 3 / Q6W0C5
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F1
Gene start: 122626410
Gene end: 122630272
  
Corresponding Affymetrix probe sets: 10541515 (MoGene1.0st)   10604135 (MoGene1.0st)   1424295_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062832
Ensembl peptide - ENSMUSP00000115252
NCBI entrez gene - 73708     See in Manteia.
MGI - MGI:1920958
RefSeq - NM_139218
RefSeq Peptide - NP_631964
swissprot - K4DID3
swissprot - Q8QZY3
Ensembl - ENSMUSG00000046323
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DPPA3ENSG00000187569Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029096  Developmental pluripotency-associated protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0040016 embryonic cleavage IMP
 biological_processGO:0044726 protection of DNA demethylation of female pronucleus IMP
 biological_processGO:1901536 negative regulation of DNA demethylation IMP
 biological_processGO:2000653 regulation of genetic imprinting IMP
 cellular_componentGO:0001939 female pronucleus IDA
 cellular_componentGO:0001940 male pronucleus IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035064 methylated histone binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Hsf1tm1Anak/Hsf1tm1Anak,Hsf4tm1Anak/Hsf4tm1Anak
Genetic Background: involves: C57BL/6 * CBA * ICR

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: St14tm1Bug/St14tm1Bug
Genetic Background: involves: 129P2/OlaHsd

 MP:0003406 failure of zygotic cell division "inability of a fertilized oocyte to initiate or complete early cell divisions" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Irx6tm1Chow/Irx6tm1Chow,Vsx1tm1Mci/Vsx1tm1Mci
Genetic Background: involves: 129S1/Sv * 129S1/SvImj * 129X1/SvJ

 MP:0003718 maternal effect "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: St14tm1Bug/St14tm1Bug
Genetic Background: involves: 129P2/OlaHsd

 MP:0008877 abnormal DNA methylation "any anomaly in the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine of DNA" [GO:0006306]
Show

Allelic Composition: Irx6tm1Chow/Irx6tm1Chow,Vsx1tm1Mci/Vsx1tm1Mci
Genetic Background: involves: 129S1/Sv * 129S1/SvImj * 129X1/SvJ

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Npm1tm1Gsva/Npm1tm1Gsva,Dppa3tm1(cre)Peli/Dppa3+
Genetic Background: involves: 129S5/SvEvBrd * 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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