Manteia

ENSMUSG00000046727

Mus musculus

Features

Gene ID:	ENSMUSG00000046727

Biological name :	Cystm1

Synonyms :	Cysteine-rich and transmembrane domain-containing protein 1 / Cystm1 / Q8K353

Possible biological names infered from orthology :	cysteine rich transmembrane module containing 1 / Q9H1C7

Species:	Mus musculus

Chr. number:	18
Strand:	1
Band:	B2
Gene start:	36345619
Gene end:	36402980

Corresponding Affymetrix probe sets:	10454881 (MoGene1.0st) 1427878_at (Mouse Genome 430 2.0 Array) 1441883_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000114199 Ensembl peptide - ENSMUSP00000129683 Ensembl peptide - ENSMUSP00000115138 Ensembl peptide - ENSMUSP00000051708 NCBI entrez gene - 66060 See in Manteia. MGI - MGI:1913310 RefSeq - NM_001081365 RefSeq Peptide - NP_001074834 swissprot - D3YVS7 swissprot - F5H8M7 swissprot - D3YWV2 swissprot - Q8K353 Ensembl - ENSMUSG00000046727

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
A5PLE2	ENSDARG00000102482	Danio rerio
si:ch211-160j14.2	ENSDARG00000073961	Danio rerio
CYSTM1	ENSGALG00000036310	Gallus gallus
CYSTM1	ENSG00000120306	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID

Name

No match

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0003674	molecular_function	ND

Pathways (from Reactome)

Pathway description

Neutrophil degranulation

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001303	abnormal lens morphology	"malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0002644	decreased circulating triglyceride level	"lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0002757	reduced vertical activity	"lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0002968	increased circulating alkaline phosphatase level	"elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0003961	decreased lean body mass	"less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0005387	immune system phenotype		Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0010024	increased total body fat amount	"greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0010379	decreased respiratory quotient	"reduction in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0011940	decreased food intake	"reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0013520	increased CD4-positive NK T cell number	"increase in the number of CD4-positive NK T cells" [MGI:Saran]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp
MP:0013523	increased memory-marker CD4-positive NK T cell number	"increase in the number of memory-marker CD4-positive NK T cells with a CD44+ CD62L- phenotype" [MGI:Saran]	Show Allelic Composition: Cyp27b1^{tm1b(EUCOMM)Hmgu}/Cyp27b1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Cyp27b1^{tm1b(EUCOMM)Hmgu}/Tcp

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr