ENSMUSG00000046753


Mus musculus

Features
Gene ID: ENSMUSG00000046753
  
Biological name :Ccdc66
  
Synonyms : Ccdc66 / Coiled-coil domain-containing protein 66 / Q6NS45
  
Possible biological names infered from orthology : A2RUB6 / coiled-coil domain containing 66
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: A3
Gene start: 27481090
Gene end: 27508460
  
Corresponding Affymetrix probe sets: 10418275 (MoGene1.0st)   1442982_at (Mouse Genome 430 2.0 Array)   1443920_at (Mouse Genome 430 2.0 Array)   1447469_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052546
Ensembl peptide - ENSMUSP00000153023
NCBI entrez gene - 320234     See in Manteia.
MGI - MGI:2443639
RefSeq - XM_017316057
RefSeq - NM_177111
RefSeq - XM_011245087
RefSeq - XM_011245088
RefSeq - XM_006519127
RefSeq - XM_006519131
RefSeq Peptide - NP_796085
swissprot - Q6NS45
Ensembl - ENSMUSG00000046753
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCDC66ENSGALG00000005450Gallus gallus
 A2RUB6ENSG00000180376Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046548 retinal rod cell development IMP
 biological_processGO:0050908 detection of light stimulus involved in visual perception IMP
 biological_processGO:0060060 post-embryonic retina morphogenesis in camera-type eye IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001005 abnormal rod morphology "structural or developmental anomaly of the photoreceptors that contain rhodopsin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0003728 abnormal photoreceptor layer "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0003729 abnormal photoreceptor outer segments "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0003730 abnormal photoreceptor inner segments "malformation/anomalous structure of the photoreceptor layer which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0008444 retinal cone cell degeneration "a retrogressive impairment of function or destruction of one of the photoreceptor cell types in the retina, in which the photopigment is in invaginations of the cell membrane of the outer segment" [MESH:A08.663.650.650.670.100, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0008450 retinal photoreceptor degeneration "a retrogressive impairment of function or destruction of a cell specialized to detect and transduce light, including rods and cones of the retina" [MESH:A08.663.650.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0008451 retinal rod cell degeneration "a retrogressive impairment of function or destruction of one of the photoreceptor cell types of the vertebrate retina, in which the photopigment is in stacks of membranous disks separate from the outer cell membrane" [MESH:A08.663.650.650.670.650]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Csn1s1tm1Afk/Csn1s1+
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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