ENSMUSG00000046846


Mus musculus

Features
Gene ID: ENSMUSG00000046846
  
Biological name :Spesp1
  
Synonyms : Q9D5A0 / Sperm equatorial segment protein 1 / Spesp1
  
Possible biological names infered from orthology : Q6UW49
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: B
Gene start: 62270729
Gene end: 62282208
  
Corresponding Affymetrix probe sets: 10594297 (MoGene1.0st)   1420366_at (Mouse Genome 430 2.0 Array)   1449837_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058522
NCBI entrez gene - 66712     See in Manteia.
MGI - MGI:1913962
RefSeq - NM_025721
RefSeq Peptide - NP_079997
swissprot - Q9D5A0
Ensembl - ENSMUSG00000046846
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6UW49ENSG00000258484Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026743  Sperm equatorial segment protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007340 acrosome reaction IMP
 biological_processGO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization IMP
 biological_processGO:0009566 fertilization IDA
 biological_processGO:0035036 sperm-egg recognition IDA
 cellular_componentGO:0001669 acrosomal vesicle IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Cdc20Gt(XE368)Byg/Cdc20tm1Jvd
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

Allelic Composition: Spesp1tm1Osb/Spesp1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005411 delayed fertilization "a lag in the normal time of onset of the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdc20Gt(XE368)Byg/Cdc20tm1Jvd
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

 MP:0008898 abnormal acrosome morphology "any structural anomaly of the cap-like structure at the anterior end of the sperm head that produces enzymes needed for egg penetration" [MESH:A05.360.490.890.820.100]
Show

Allelic Composition: Cdc20Gt(XE368)Byg/Cdc20tm1Jvd
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

 MP:0009647 decreased fertilization frequency "he number of secondary oocytes each penetrated by a spermatozoon followed by fusion of the male and female pronuclei are fewer than expected" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdc20Gt(XE368)Byg/Cdc20tm1Jvd
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

Allelic Composition: Spesp1tm1Osb/Spesp1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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