| MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0000852 | small cerebellum | "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0000872 | abnormal external granule cell layer | "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0000889 | abnormal cerebellar molecular layer | "any malformation or absence of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0001393 | ataxia | "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0001488 | increased startle reflex | "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dnmt3atm1b(KOMP)Wtsi/Dnmt3atm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnmt3atm1b(KOMP)Wtsi/J
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| MP:0001513 | limb grasping | "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0001525 | impaired balance | "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0002175 | low brain weight | "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0006009 | abnormal neuronal migration | "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0010053 | decreased grip strength | "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: Dnmt3atm1b(KOMP)Wtsi/Dnmt3atm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnmt3atm1b(KOMP)Wtsi/J
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Sprr3tm1.1Ppy/Sprr3tm1.1Ppy
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J * SJL
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| MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
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Allelic Composition: Dnmt3atm1b(KOMP)Wtsi/Dnmt3atm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnmt3atm1b(KOMP)Wtsi/J
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